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View Structure Prediction Details

Protein: MCA6_ARATH
Organism: Arabidopsis thaliana
Length: 368 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MCA6_ARATH.

Description E-value Query
Range
Subject
Range
MCA5_ARATH - Metacaspase-5 OS=Arabidopsis thaliana GN=AMC5 PE=1 SV=1
327.0 [0..1] [368..1]

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Predicted Domain #1
Region A:
Residues: [1-157]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKKALLIGI NYVGTKAELR GCVNDVRRMR ISLVERYGFS EENIKMLIDT DSSSIKPTGK  60
   61 NIRQALLDLV EPAKSGDVLF VHYSGHGTRL PAETGEDDDT GYDECIVPSD MNLITDDDFR 120
  121 DLVDMVPKDC PITIISDSCH SGGLIDEAKE QIGESTK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.221849
Match: 1rwkA
Description: Crystal structure of human caspase-1 in complex with 3-(2-mercapto-acetylamino)-4-oxo-pentanoic acid
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [158-368]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KKKDSGDSST INKETEAEII EVGNRSLPLE TLIDMLKQET GNDDIEVGKI RTTLFDMFGD  60
   61 DSSPKVKKFM NVILSNLQET TTTIQTVSDE VLGSVENLAQ EFLEQKLSDD VKPAIQDVYA 120
  121 GAINGALPDN GILISGCQTD QTSSDASPPG HPELAYGALT NAIQIIIGET KGKISNKDLV 180
  181 LKARKLLRKQ GFDQRPGLYC NDAYVNARFI C

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.0
Match: 1jxqA
Description: Caspase-9
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.446816200197746 bayes_pls_golite062009
binding 0.128865592323915 bayes_pls_golite062009
hydrolase activity 0.00345801703057891 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle