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View Structure Prediction Details

Protein: E2FB_ARATH
Organism: Arabidopsis thaliana
Length: 469 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for E2FB_ARATH.

Description E-value Query
Range
Subject
Range
gi|11125655 - gi|11125655|emb|CAC15485.1| E2F-related protein [Arabidopsis thaliana]
504.0 [0..1] [469..1]
gi|22086269 - gi|22086269|gb|AAM90620.1|AF400000_1 E2F-related transcription factor 1 [Thlaspi caerulescens]
419.0 [0..2] [469..4]
gi|215697038, gi... - gi|56202337|dbj|BAD73815.1| putative E2F homolog [Oryza sativa Japonica Group], gi|215697038|dbj|BAG...
384.0 [0..4] [460..2]
gi|11558192 - gi|11558192|emb|CAC17702.1| transcription factor (E2F) [Chenopodium rubrum]
384.0 [0..7] [465..11]
gi|8977833 - gi|8977833|emb|CAB95727.1| transcription factor E2F [Daucus carota]
379.0 [0..23] [461..1]
gi|6328415 - gi|6328415|dbj|BAA86386.1| transcription factor [Nicotiana tabacum]
375.0 [0..7] [465..2]
gi|5763821 - gi|5763821|emb|CAB53258.1| E2F protein [Triticum sp.]
370.0 [0..7] [457..5]
gi|50251979 - gi|50251979|dbj|BAD27913.1| E2F homolog [Oryza sativa Japonica Group]
gi|12225043 - gi|12225043|dbj|BAB20932.1| E2F homolog [Oryza sativa]
366.0 [0..55] [460..32]

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Predicted Domain #1
Region A:
Residues: [1-92]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEEVPQQFP SSKRQLHPSL SSMKPPLVAP GEYHRFDAAE TRGGGAVADQ VVSDAIVIKS  60
   61 TLKRKTDLVN QIVEVNELNT GVLQTPVSGK GG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.404 N/A N/A a.60.7 5' to 3' exonuclease, C-terminal subdomain
View Download 0.404 N/A N/A a.60.7 5' to 3' exonuclease, C-terminal subdomain
View Download 0.343 N/A N/A d.58.4 Dimeric alpha+beta barrel
View Download 0.343 N/A N/A d.58.4 Dimeric alpha+beta barrel
View Download 0.305 N/A N/A a.39.1 EF-hand
View Download 0.305 N/A N/A a.39.1 EF-hand
View Download 0.299 N/A N/A d.58.58 Description not found.
View Download 0.291 N/A N/A d.79.3 L30e-like
View Download 0.263 N/A N/A a.81.1 N-terminal domain of DnaB helicase

Predicted Domain #2
Region A:
Residues: [93-194]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KAKKTSRSAK SNKSGTLASG SNAGSPGNNF AQAGTCRYDS SLGLLTKKFI NLIKQAEDGI  60
   61 LDLNKAADTL EVQKRRIYDI TNVLEGIGLI EKTLKNRIQW KG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 23.0
Match: 1cf7A
Description: Cell cycle transcription factor E2F-4
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [195-397]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LDVSKPGETI ESIANLQDEV QNLAAEEARL DDQIRESQER LTSLSEDENN KRLLFVTEND  60
   61 IKNLPCFQNK TLIAVKAPHG TTLEVPDPDE AGGYQRRYRI ILRSTMGPID VYLVSQFEES 120
  121 FEDIPQADEP SNVPDEPSNV PDVPSNLPST SGLPENHDVS MPMKEESTER NMETQEVDDT 180
  181 QRVYSDIESH DFVDGIMKIV PPD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 37.154902
Match: 2azeA
Description: Structure of the Rb C-terminal domain bound to an E2F1-DP1 heterodimer
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [398-469]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LDMGVDYWFR SEVGEVSITD MWPDESGPDW NQMITFDQDH AGPSDNKILE QPQTPSSPTP  60
   61 EESTATRSPT GS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.574 d.15.2 CAD & PB1 domains
View Download 0.475 d.15.1 Ubiquitin-like
View Download 0.475 d.15.1 Ubiquitin-like
View Download 0.438 d.15.1 Ubiquitin-like
View Download 0.412 a.4.5 "Winged helix" DNA-binding domain
View Download 0.401 d.15.2 CAD & PB1 domains
View Download 0.400 d.15.1 Ubiquitin-like
View Download 0.386 d.43.1 Elongation factor Ts (EF-Ts), dimerisation domain
View Download 0.313 d.15.1 Ubiquitin-like
View Download 0.302 b.40.4 Nucleic acid-binding proteins
View Download 0.297 d.15.1 Ubiquitin-like
View Download 0.241 b.40.4 Nucleic acid-binding proteins
View Download 0.218 a.159.5 Description not found.


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