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View Structure Prediction Details

Protein: LRP6C_ARATH
Organism: Arabidopsis thaliana
Length: 455 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LRP6C_ARATH.

Description E-value Query
Range
Subject
Range
gi|1082703, gi|6... - gi|693937|emb|CAA88401.1| polyadenylate binding protein II [Homo sapiens], pir||S52491 polyadenylate...
247.0 [0..82] [455..24]

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Predicted Domain #1
Region A:
Residues: [1-130]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAQMQREEVE SVTTEKKRLD GGGGSSGAQA TAFKFNAQAP EFVPRSHTTA PAPQVSPVSG  60
   61 YFYPCFHYNG GCIGGCGGGV CGGGGTGVGT QSSDWIYVGG GDPTAQHQHV HDPAAAFYIS 120
  121 NPAVQFPASQ 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [131-335]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NSSSSSKNLL SDDLRLKIVK QVEYQFTDMS LLANESISKH ISKDPEGYVP VSYIASTKKI  60
   61 KALTSNHHLV SLALRSSSKL VVSEDGKKVK RTSQFTDRDR EELQGRTVVA ENLPDDHSYQ 120
  121 NLEKIFGVVG NVKAIRICHP PESNSSRPKG DFLMSNKIHA LIEYDNTVIA DKAVEKLNDE 180
  181 RNWRKGLRVR LLLRCSPKSV LKNRR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 39.0
Match: 1po6A
Description: Crystal Structure of UP1 Complexed With d(TAGG(6MI)TTAGGG): A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6MI)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.950788308762215 bayes_pls_golite062009
nucleic acid binding 0.29562225149076 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [336-455]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NFDGILIDDE LPSYESGEDS PRLHLTESQL DNDGDDNNVG GLWGKGRGKG RGRSPRSYAV  60
   61 GGGGRSFGIG LGVSLGIPSL GSHESSSPKT ATKGPRMPDG TRGFTMGRGK PSISLSPNNL 120
  121 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 29.522879
Match: 3sxlA
Description: Sex-lethal protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.950788308762215 bayes_pls_golite062009
nucleic acid binding 0.29562225149076 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle