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View Structure Prediction Details

Protein: PEX5_ARATH
Organism: Arabidopsis thaliana
Length: 728 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PEX5_ARATH.

Description E-value Query
Range
Subject
Range
gi|73670079, gi|... - gi|73670079|ref|YP_306094.1| TPR repeat-containing protein [Methanosarcina barkeri str. Fusaro], gi|...
386.0 [0..2] [728..195]
gi|33640682, gi|... - gi|33862569|ref|NP_894129.1| TPR repeat-containing protein [Prochlorococcus marinus str. MIT 9313], ...
378.0 [0..2] [728..316]
gi|11358612, gi|... - gi|3603353|gb|AAC62012.1| peroxisomal targeting signal type 1 receptor [Arabidopsis thaliana], pir||...
368.0 [0..1] [728..1]
gi|113475191, gi... - gi|113475191|ref|YP_721252.1| glycosyl transferase family protein [Trichodesmium erythraeum IMS101],...
366.0 [0..135] [726..14]
gi|118385554 - gi|118385554|ref|XP_001025906.1| TPR Domain containing protein [Tetrahymena thermophila]
gi|89307673, gi|... - gi|89307673|gb|EAS05661.1| TPR Domain containing protein [Tetrahymena thermophila SB210], gi|1183855...
366.0 [0..38] [727..346]
gi|82879857 - gi|82879857|gb|ABB92565.1| peroxisomal import receptor PTS1 [Brassica napus]
354.0 [0..1] [728..1]
gi|20093095, gi|... - gi|20093095|ref|NP_619170.1| TPR domain-containing protein [Methanosarcina acetivorans C2A], gi|1991...
328.0 [0..7] [728..247]

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Predicted Domain #1
Region A:
Residues: [1-107]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAMRDLVNGG AACAVPGSSS SSNPLGALTN ALLGSSSKTQ ERLKEIPNAN RSGPRPQFYS  60
   61 EDQQIRSLPG SELDQPLLQP GAQGSEFFRG FRSVDQNGLG AAWDEVQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [108-587]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QGGPMPPMGP MFEPVQPTFE GPPQRVLSNF LHSFVESSRG GIPFRPAPVP VLGLSQSDKQ  60
   61 CIRDRSSIMA RHFFADRGEE FINSQVNALL SSLDIDDGIQ ARGHVPGRFR ELDDYWNESQ 120
  121 AVVKPNLHPA DNWAAEFNQH GMDHGGPDSW VQSFEQQHGV NGWATEFEQG QSQLMSSQMR 180
  181 SMDMQNIAAM EQTRKLAHTL SQDGNPKFQN SRFLQFVSKM SRGELIIDEN QVKQASAPGE 240
  241 WATEYEQQYL GPPSWADQFA NEKLSHGPEQ WADEFASGRG QQETAEDQWV NEFSKLNVDD 300
  301 WIDEFAEGPV GDSSADAWAN AYDEFLNEKN AGKQTSGVYV FSDMNPYVGH PEPMKEGQEL 360
  361 FRKGLLSEAA LALEAEVMKN PENAEGWRLL GVTHAENDDD QQAIAAMMRA QEADPTNLEV 420
  421 LLALGVSHTN ELEQATALKY LYGWLRNHPK YGAIAPPELA DSLYHADIAR LFNEASQLNP 480
  481 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.221849
Match: 2ooeA
Description: No description for 2ooeA was found.

Predicted Domain #3
Region A:
Residues: [588-637]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EDADVHIVLG VLYNLSREFD RAITSFQTAL QLKPNDYSLW NKLGATQANS 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 51.69897
Match: 1w3bA
Description: The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [638-728]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VQSADAISAY QQALDLKPNY VRAWANMGIS YANQGMYKES IPYYVRALAM NPKADNAWQY  60
   61 LRLSLSCASR QDMIEACESR NLDLLQKEFP L

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 28.30103
Match: 2j9qA
Description: No description for 2j9qA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle