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View Structure Prediction Details

Protein: HEC1_ARATH
Organism: Arabidopsis thaliana
Length: 241 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HEC1_ARATH.

Description E-value Query
Range
Subject
Range
gi|41349732 - gi|41349732|dbj|BAD08297.1| microphthalmia-associated transcription factor type M [Xenopus laevis]
125.0 [0..1] [240..46]

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Predicted Domain #1
Region A:
Residues: [1-124]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSDIMNMMM HQMEKLPEFC NPNSSFFSPD HNNTYPFLFN STHYQSDHSM TNEPGFRYGS  60
   61 GLLTNPSSIS PNTAYSSVFL DKRNNSNNNN NGTNMAAMRE MIFRIAVMQP IHIDPEAVKP 120
  121 PKRR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [125-241]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NVRISKDPQS VAARHRRERI SERIRILQRL VPGGTKMDTA SMLDEAIHYV KFLKKQVQSL  60
   61 EEQAVVTGGG GGGGGRVLIG GGGMTAASGG GGGGGVVMKG CGTVGTHQMV GNAQILR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.0
Match: 1am9A
Description: SREBP-1a
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.12507195426228 bayes_pls_golite062009
nucleic acid binding 0.43204604575196 bayes_pls_golite062009
DNA binding 0.40884226851256 bayes_pls_golite062009
transcription regulator activity 0.31759335140578 bayes_pls_golite062009
transcription factor activity 0.09721565916723 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle