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View Structure Prediction Details

Protein: EIN4_ARATH
Organism: Arabidopsis thaliana
Length: 766 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EIN4_ARATH.

Description E-value Query
Range
Subject
Range
gi|145411509 - gi|145411509|gb|ABP68413.1| putative ethylene receptor [Cucumis melo]
ETR1_CUCMN - Ethylene receptor 1 OS=Cucumis melo var. cantalupensis GN=ETR1 PE=2 SV=1
571.0 [0..24] [764..1]

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Predicted Domain #1
Region A:
Residues: [1-336]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRSLGLGLL LFALLALVSG DNDYVSCNCD DEGFLSVHTI LECQRVSDLL IAIAYFSIPL  60
   61 ELLYFISFSN VPFKWVLVQF IAFIVLCGMT HLLNAWTYYG PHSFQLMLWL TIFKFLTALV 120
  121 SCATAITLLT LIPLLLKWKV RELYLKQNVL ELNEEVGLMK RQKEMSVQVR MLTREIRKSL 180
  181 DKHMILRTTL VELSKILDLQ NSAVWMPNEN RTEMHLTHEL RANPMRSFRV IPINDPDVVQ 240
  241 VRETKVVTIL RKNSVLAVES SGCGGSEEFG PVAAIRMPML HGLNFKGGTP EFVDTPYAIM 300
  301 VLVLPSANSR VWTDKEIEIA EVVADQVAVA ISHASV

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.16
Match: 1ykdA
Description: Crystal Structure of the Tandem GAF Domains from a Cyanobacterial Adenylyl Cyclase: Novel Modes of Ligand-Binding and Dimerization
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [337-622]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LEESQLMREK LGIQNRALLR AKQNAMMASQ ARNTCQKVMS HGMRRPMHTI LGLLSMFQSE  60
   61 SMSLDQKIIV DALMKTSTVL SALINDVIDI SPKDNGKSAL EVKRFQLHSL IREAACVAKC 120
  121 LSVYKGYGFE MDVQTRLPNL VVGDEKRTFQ LVMYMLGYIL DMTDGGKTVT FRVICEGTGT 180
  181 SQDKSKRETG MWKSHMSDDS LGVKFEVEIN EIQNPPLDGS AMAMRHIPNR RYHSNGIKEG 240
  241 LSLGMCRKLA QMMQGNIWIS PKSHGQTQSM QLVLRFQTRP SIRRSI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 49.39794
Match: 2c2aA
Description: Structure of the entire cytoplasmic portion of a sensor histidine kinase protein
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [623-766]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LAGNAPELQH PNSNSILRGL RITLADDDDV NRTVTKRLLE KLGCEVTAVS SGFECLNALS  60
   61 NVEMSYRVVI LDLQMPEMDG FEVAMKIRKF CGHHWPLIIA LTASTEDHVR ERCLQMGMNG 120
  121 MIQKPVLLHV MASELRRALQ TASE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.69897
Match: 1dcfA
Description: Receiver domain of the ethylene receptor
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
two-component response regulator activity 7.02872640261738 bayes_pls_golite062009
signal transducer activity 4.51666042720644 bayes_pls_golite062009
molecular transducer activity 4.51666042720644 bayes_pls_golite062009
transcription regulator activity 3.44888100104099 bayes_pls_golite062009
protein histidine kinase activity 2.35011582062573 bayes_pls_golite062009
two-component sensor activity 2.32303301074957 bayes_pls_golite062009
phosphotransferase activity, nitrogenous group as acceptor 2.28838869071567 bayes_pls_golite062009
binding 1.22427537074115 bayes_pls_golite062009
DNA binding 1.11037597107903 bayes_pls_golite062009
nucleic acid binding 0.93151849951839 bayes_pls_golite062009
transcription factor activity 0.62886970109503 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle