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View Structure Prediction Details

Protein: gi|1146165, gi|1...
Organism: Arabidopsis thaliana
Length: 369 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|1146165, gi|1....

Description E-value Query
Range
Subject
Range
gi|196158491, gi... - gi|88794338|ref|ZP_01110047.1| uroporphyrin-III C-methyltransferase [Alteromonas macleodii 'Deep eco...
358.0 [0..2] [360..133]

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Predicted Domain #1
Region A:
Residues: [1-369]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALVQRIPIS SSSIRNWQQA RTNLTPICCL HYNTASSSSS PFTEKHSVER YQRDQWLYKA  60
   61 VEPTPPSTPS PSPFEDEVFV RENDIASQLP ELKKLLAVLK EKRVKGCKGG DCGPGDVYLV 120
  121 GTGPGDPELL TLKAVRVIQS ADLLLYDRLV SNDVLELVAP DARLLYVGKT AGYHSRTQEE 180
  181 IHELLLNFAE AGATVVRLKG GDPLVFGRGG EEMDFLQQQG IRVQVIPGIT AASGIAAELG 240
  241 IPLTHRGVAT SVRFLTGHSR KGGTDPLFVA ENAADPDTTL VVYMGLGTLP SLAQKLMDHG 300
  301 LPSDTPAVAV ERGTTPLQRT VFAELKDFAT EIQSAGLVSP TLIIIGKVVE LSPLWPHCTK 360
  361 ESSCLVETR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 90.0
Match: 1pjqA
Description: Structure and function of CysG, the multifunctional methyltransferase/dehydrogenase/ferrochelatase for siroheme synthesis
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
uroporphyrin-III C-methyltransferase activity 3.573271502205 bayes_pls_golite062009
C-methyltransferase activity 3.35393353163232 bayes_pls_golite062009
precorrin-4 C11-methyltransferase activity 2.18371138649366 bayes_pls_golite062009
catalytic activity 1.48349578618275 bayes_pls_golite062009
transferase activity 0.912524944496351 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 0.431791521097299 bayes_pls_golite062009
methyltransferase activity 0.424918406685891 bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity 0.28351517300952 bayes_pls_golite062009
uroporphyrinogen-III synthase activity 0.00871858903098705 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle