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View Structure Prediction Details

Protein: FPG_ARATH
Organism: Arabidopsis thaliana
Length: 390 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FPG_ARATH.

Description E-value Query
Range
Subject
Range
gi|85706182, gi|... - gi|85706182|ref|ZP_01037277.1| formamidopyrimidine-DNA glycosylase [Roseovarius sp. 217], gi|8566934...
351.0 [0..1] [277..1]

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Predicted Domain #1
Region A:
Residues: [1-278]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPELPEVEAA RRAIEENCLG KKIKRVIIAD DNKVIHGISP SDFQTSILGK TIISARRKGK  60
   61 NLWLELDSPP FPSFQFGMAG AIYIKGVAVT KYKRSAVKDS EEWPSKYSKF FVELDDGLEL 120
  121 SFTDKRRFAK VRLLANPTSV SPISELGPDA LLEPMTVDEF AESLAKKKIT IKPLLLDQGY 180
  181 ISGIGNWIAD EVLYQARIHP LQTASSLSKE QCEALHTSIK EVIEKAVEVD ADSSQFPSYW 240
  241 IFHNREKKPG KAFVDGKKID FITAGGRTTA YVPELQKL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 88.045757
Match: 1k82A
Description: DNA repair protein MutM (Fpg)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
DNA N-glycosylase activity 4.06377793944255 bayes_pls_golite062009
oxidized base lesion DNA N-glycosylase activity 3.68895100180378 bayes_pls_golite062009
hydrolase activity, hydrolyzing N-glycosyl compounds 3.63831813037192 bayes_pls_golite062009
oxidized purine base lesion DNA N-glycosylase activity 3.50273405950314 bayes_pls_golite062009
DNA-(apurinic or apyrimidinic site) lyase activity 3.32722481172627 bayes_pls_golite062009
hydrolase activity 2.63663177929964 bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds 2.59048389792519 bayes_pls_golite062009
binding 1.7313696856499 bayes_pls_golite062009
DNA binding 1.22619720972604 bayes_pls_golite062009
nucleic acid binding 1.17199530230795 bayes_pls_golite062009
transcription regulator activity 1.16376707327858 bayes_pls_golite062009
protein binding 1.14219782236887 bayes_pls_golite062009
transcription factor activity 0.472763834470731 bayes_pls_golite062009
carbon-oxygen lyase activity 0.438176855290553 bayes_pls_golite062009
catalytic activity 0.101795606736461 bayes_pls_golite062009
lyase activity 0.0836281676510939 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [279-390]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YGKDAEKAAK VRPAKRGVKP KEDDGDGEED EQETEKEDES AKSKKGQKPR GGRGKKPASK  60
   61 TKTEESDDDG DDSEAEEEVV KPKGRGTKPA IKRKSEEKAT SQAGKKPKGR KS

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.52
Match: 2j63A
Description: No description for 2j63A was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle