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View Structure Prediction Details

Protein: SYNC2_ARATH
Organism: Arabidopsis thaliana
Length: 638 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SYNC2_ARATH.

Description E-value Query
Range
Subject
Range
SYD_PHOLL - Aspartate--tRNA ligase OS=Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP 105565 /...
SYD_PHOLL - Aspartyl-tRNA synthetase OS=Photorhabdus luminescens subsp. laumondii GN=aspS PE=3 SV=1
471.0 [0..108] [636..2]

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Predicted Domain #1
Region A:
Residues: [1-106]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MESHGKTHQK EHDNDLSPKP ITLSKYSKRV ELKTLLDRSD RGAGLAGKRV VIGGWVKSAR  60
   61 AVKKNSPPPP LPVVAAPSPS SGGDQAHTTA NIRCTEIIQS KMNIFK

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.3
Match: 1e1oA
Description: Lysyl-tRNA synthetase (LysRS)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ligase activity, forming carbon-oxygen bonds 2.74078236174851 bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds 2.74078236174851 bayes_pls_golite062009
aminoacyl-tRNA ligase activity 2.7278767226117 bayes_pls_golite062009
ligase activity 2.0946092938039 bayes_pls_golite062009
nucleic acid binding 1.45331399659589 bayes_pls_golite062009
structural constituent of ribosome 1.29373500798813 bayes_pls_golite062009
structural molecule activity 1.03774215013842 bayes_pls_golite062009
binding 0.819455487357477 bayes_pls_golite062009
DNA binding 0.732939214265147 bayes_pls_golite062009
translation regulator activity 0.515944241286305 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.469391077412475 bayes_pls_golite062009
aspartate-tRNA ligase activity 0.0258496208950199 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [107-638]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RFFDVLSGGG KTYPIFDKTE LAGQKAVPPP EYVFYFLISD GSSISSLQVV VDSALSTVPA  60
   61 TQLMALGTCI VAEGVLRLPL AASAKHVIEL EAEKLLHVGT VDPEKYPLSK KQLPLHMLRD 120
  121 FSHFRPRTTT VGSVTRVHSA LTLASHTFLQ YHGFQYVQVP VITTTTGFGE MFRVTTLLGK 180
  181 TDDKEEKKPP VQEKDGFSID TVKAVIKEKT RLIDHLKRSD SNRETVVAAV HDLKKTNDLA 240
  241 SQIEMKQKSK TGTLVKPEKL DFSKDFFGRD TYLTASGRFH LESYASALGK VYTFGPRFIA 300
  301 DKIDNARHLA EKWNVETEMA FAELDDAMDC ADEYFKFLCK YVLENRDEDM KFISKRVDKT 360
  361 ITTRLEATAS SSLLRFSYTE VISLLQKATT TKFETKPEWG VALTTEHLSY LTDEIYKGPV 420
  421 IVHTYPKAIK QFYVRLNDDK KTVAAFDLVV PKVGVVITGS QNEERFEILD ARIGESGFTR 480
  481 EKFEWYLDLR RHGTVKHSGI SLSMEQMLLY ATGLPDIKDA IPFPRSWGKA NN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 129.0
Match: 1c0aA
Description: Aspartyl-tRNA synthetase (AspRS); Prokaryotic AspRS, insert domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ligase activity, forming carbon-oxygen bonds 7.20130208252979 bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds 7.20130208252979 bayes_pls_golite062009
aminoacyl-tRNA ligase activity 7.18884532579969 bayes_pls_golite062009
ligase activity 6.46734856052643 bayes_pls_golite062009
asparagine-tRNA ligase activity 4.88411901093713 bayes_pls_golite062009
catalytic activity 2.36416267096403 bayes_pls_golite062009
phenylalanine-tRNA ligase activity 1.82630084735103 bayes_pls_golite062009
serine-tRNA ligase activity 1.67995723068335 bayes_pls_golite062009
threonine-tRNA ligase activity 1.61348476813499 bayes_pls_golite062009
structural constituent of ribosome 1.48826676464117 bayes_pls_golite062009
histidine-tRNA ligase activity 1.44658852946316 bayes_pls_golite062009
alanine-tRNA ligase activity 1.37855221028045 bayes_pls_golite062009
lysine-tRNA ligase activity 1.2286808923607 bayes_pls_golite062009
glycine-tRNA ligase activity 1.22845858760023 bayes_pls_golite062009
structural molecule activity 1.20191382777151 bayes_pls_golite062009

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