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View Structure Prediction Details

Protein: MEDEA_ARATH
Organism: Arabidopsis thaliana
Length: 689 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MEDEA_ARATH.

Description E-value Query
Range
Subject
Range
gi|109068768 - gi|109068768|ref|XP_001097572.1| PREDICTED: enhancer of zeste 2 [Macaca mulatta]
404.0 [0..7] [665..174]

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Predicted Domain #1
Region A:
Residues: [1-142]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEKENHEDDG EGLPPELNQI KEQIEKERFL HIKRKFELRY IPSVATHASH HQSFDLNQPA  60
   61 AEDDNGGDNK SLLSRMQNPL RHFSASSDYN SYEDQGYVLD EDQDYALEED VPLFLDEDVP 120
  121 LLPSVKLPIV EKLPRSITWV FT

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [143-295]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSSQLMAESD SVIGKRQIYY LNGEALELSS EEDEEDEEED EEEIKKEKCE FSEDVDRFIW  60
   61 TVGQDYGLDD LVVRRALAKY LEVDVSDILE RYNELKLKND GTAGEASDLT SKTITTAFQD 120
  121 FADRRHCRRC MIFDCHMHEK YEPESRSSED KSS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [296-392]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LFEDEDRQPC SEHCYLKVRS VTEADHVMDN DNSISNKIVV SDPNNTMWTP VEKDLYLKGI  60
   61 EIFGRNSCDV ALNILRGLKT CLEIYNYMRE QDQCTMS

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.989
Match: 1xc5A
Description: Solution Structure of the SMRT Deacetylase Activation Domain
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [393-689]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LDLNKTTQRH NQVTKKVSRK SSRSVRKKSR LRKYARYPPA LKKTTSGEAK FYKHYTPCTC  60
   61 KSKCGQQCPC LTHENCCEKY CGCSKDCNNR FGGCNCAIGQ CTNRQCPCFA ANRECDPDLC 120
  121 RSCPLSCGDG TLGETPVQIQ CKNMQFLLQT NKKILIGKSD VHGWGAFTWD SLKKNEYLGE 180
  181 YTGELITHDE ANERGRIEDR IGSSYLFTLN DQLEIDARRK GNEFKFLNHS ARPNCYAKLM 240
  241 IVRGDQRIGL FAERAIEEGE ELFFDYCYGP EHADWSRGRE PRKTGASKRS KEARPAR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 31.09691
Match: 2r3aA
Description: No description for 2r3aA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle