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View Structure Prediction Details

Protein: HEM3_ARATH
Organism: Arabidopsis thaliana
Length: 382 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HEM3_ARATH.

Description E-value Query
Range
Subject
Range
gi|21592624 - gi|21592624|gb|AAM64573.1| hydroxymethylbilane synthase [Arabidopsis thaliana]
528.0 [0..1] [382..1]

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Predicted Domain #1
Region A:
Residues: [1-382]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDIASSSLSQ AHKVVLTRQP SSRVNTCSLG SVSAIGFSLP QISSPALGKC RRKQSSSGFV  60
   61 KACVAVEQKT RTAIIRIGTR GSPLALAQAY ETREKLKKKH PELVEDGAIH IEIIKTTGDK 120
  121 ILSQPLADIG GKGLFTKEID EALINGHIDI AVHSMKDVPT YLPEKTILPC NLPREDVRDA 180
  181 FICLTAATLA ELPAGSVVGT ASLRRKSQIL HKYPALHVEE NFRGNVQTRL SKLQGGKVQA 240
  241 TLLALAGLKR LSMTENVASI LSLDEMLPAV AQGAIGIACR TDDDKMATYL ASLNHEETRL 300
  301 AISCERAFLE TLDGSCRTPI AGYASKDEEG NCIFRGLVAS PDGTKVLETS RKGPYVYEDM 360
  361 VKMGKDAGQE LLSRAGPGFF GN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 129.0
Match: 1ah5A
Description: REDUCED FORM SELENOMETHIONINE-LABELLED HYDROXYMETHYLBILANE SYNTHASE DETERMINED BY MAD
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 3.22743737647397 bayes_pls_golite062009
DNA binding 2.86883926687971 bayes_pls_golite062009
transcription factor activity 2.7948293378347 bayes_pls_golite062009
nucleic acid binding 2.66637887681284 bayes_pls_golite062009
binding 2.63182502368928 bayes_pls_golite062009
hydroxymethylbilane synthase activity 2.03196514141563 bayes_pls_golite062009
catalytic activity 0.674312982669564 bayes_pls_golite062009
transcription activator activity 0.050905489018976 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle