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View Structure Prediction Details

Protein: EGL1_ARATH
Organism: Arabidopsis thaliana
Length: 596 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EGL1_ARATH.

Description E-value Query
Range
Subject
Range
gi|2335192 - gi|2335192|gb|AAB72192.1| bHLH protein [Arabidopsis thaliana]
517.0 [0..1] [596..1]

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Predicted Domain #1
Region A:
Residues: [1-99]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATGENRTVP DNLKKQLAVS VRNIQWSYGI FWSVSASQPG VLEWGDGYYN GDIKTRKTIQ  60
   61 AAEVKIDQLG LERSEQLREL YESLSLAESS ASGSSQVTR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.595 d.214.1 Hypothetical protein MTH1880
View Download 0.571 d.56.1 GroEL-intermediate domain like
View Download 0.564 d.222.1 YbaB-like
View Download 0.486 d.237.1 Hypothetical protein YjiA, C-terminal domain
View Download 0.477 d.93.1 SH2 domain

Predicted Domain #2
Region A:
Residues: [100-274]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RASAAALSPE DLTDTEWYYL VCMSFVFNIG EGIPGGALSN GEPIWLCNAE TADSKVFTRS  60
   61 LLAKSASLQT VVCFPFLGGV LEIGTTEHIK EDMNVIQSVK TLFLEAPPYT TISTRSDYQE 120
  121 IFDPLSDDKY TPVFITEAFP TTSTSGFEQE PEDHDSFIND GGASQVQSWQ FVGEE

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.01
Match: 1f5mA
Description: Hypothetical protein ykl069wp
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [275-397]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ISNCIHQSLN SSDCVSQTFV GTTGRLACDP RKSRIQRLGQ IQEQSNHVNM DDDVHYQGVI  60
   61 STIFKTTHQL ILGPQFQNFD KRSSFTRWKR SSSVKTLGEK SQKMIKKILF EVPLMNKKEE 120
  121 LLP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.446 a.77.1 DEATH domain
View Download 0.286 c.44.2 Enzyme IIB-cellobiose
View Download 0.278 a.23.4 Mitochondrial import receptor subunit Tom20

Predicted Domain #4
Region A:
Residues: [398-505]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DTPEETGNHA LSEKKRREKL NERFMTLRSI IPSISKIDKV SILDDTIEYL QDLQKRVQEL  60
   61 ESCRESADTE TRITMMKRKK PDDEEERASA NCMNSKRKGS DVNVGEDE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.522879
Match: 1nkpA
Description: Myc prot-oncogene protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.12507195426228 bayes_pls_golite062009
nucleic acid binding 0.43204604575196 bayes_pls_golite062009
DNA binding 0.40884226851256 bayes_pls_golite062009
transcription regulator activity 0.31759335140578 bayes_pls_golite062009
transcription factor activity 0.09721565916723 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [506-596]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PADIGYAGLT DNLRISSLGN EVVIELRCAW REGILLEIMD VISDLNLDSH SVQSSTGDGL  60
   61 LCLTVNCKHK GTKIATTGMI QEALQRVAWI C

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.3
Match: 1zpvA
Description: ACT domain protein from Streptococcus pneumoniae
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.0923752113053079 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle