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View Structure Prediction Details

Protein: AGO1_ARATH
Organism: Arabidopsis thaliana
Length: 1048 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

No multiple sequence alignment data found for AGO1_ARATH.

Predicted Domain #1
Region A:
Residues: [1-203]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVRKRRTDAP SEGGEGSGSR EAGPVSGGGR GSQRGGFQQG GGQHQGGRGY TPQPQQGGRG  60
   61 GRGYGQPPQQ QQQYGGPQEY QGRGRGGPPH QGGRGGYGGG RGGGPSSGPP QRQSVPELHQ 120
  121 ATSPTYQAVS SQPTLSEVSP TQVPEPTVLA QQFEQLSVEQ GAPSQAIQPI PSSSKAFKFP 180
  181 MRPGKGQSGK RCIVKANHFF AEL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 32.0
Match: 1y0fB
Description: No description for 1y0fB was found.

Predicted Domain #2
Region A:
Residues: [204-346]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PDKDLHHYDV TITPEVTSRG VNRAVMKQLV DNYRDSHLGS RLPAYDGRKS LYTAGPLPFN  60
   61 SKEFRINLLD EEVGAGGQRR EREFKVVIKL VARADLHHLG MFLEGKQSDA PQEALQVLDI 120
  121 VLRELPTSRY IPVGRSFYSP DIG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [347-580]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KKQSLGDGLE SWRGFYQSIR PTQMGLSLNI DMSSTAFIEA NPVIQFVCDL LNRDISSRPL  60
   61 SDADRVKIKK ALRGVKVEVT HRGNMRRKYR ISGLTAVATR ELTFPVDERN TQKSVVEYFH 120
  121 ETYGFRIQHT QLPCLQVGNS NRPNYLPMEV CKIVEGQRYS KRLNERQITA LLKVTCQRPI 180
  181 DREKDILQTV QLNDYAKDNY AQEFGIKIST SLASVEARIL PPPWLKYHES GREG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 45.39794
Match: 1r4kA
Description: Solution Structure of the Drosophila Argonaute 1 PAZ Domain
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [581-669]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TCLPQVGQWN MMNKKMINGG TVNNWICINF SRQVQDNLAR TFCQELAQMC YVSGMAFNPE  60
   61 PVLPPVSARP EQVEKVLKTR YHDATSKLS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [670-836]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QGKEIDLLIV ILPDNNGSLY GDLKRICETE LGIVSQCCLT KHVFKMSKQY MANVALKINV  60
   61 KVGGRNTVLV DALSRRIPLV SDRPTIIFGA DVTHPHPGED SSPSIAAVVA SQDWPEITKY 120
  121 AGLVCAQAHR QELIQDLFKE WKDPQKGVVT GGMIKELLIA FRRSTGH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.0
Match: 1w9hA
Description: The Structure of a Piwi protein from Archaeoglobus fulgidus.
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [837-1048]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPLRIIFYRD GVSEGQFYQV LLYELDAIRK ACASLEAGYQ PPVTFVVVQK RHHTRLFAQN  60
   61 HNDRHSVDRS GNILPGTVVD SKICHPTEFD FYLCSHAGIQ GTSRPAHYHV LWDENNFTAD 120
  121 GLQSLTNNLC YTYARCTRSV SIVPPAYYAH LAAFRARFYM EPETSDSGSM ASGSMARGGG 180
  181 MAGRSTRGPN VNAAVRPLPA LKENVKRVMF YC

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.522879
Match: 3dlbA
Description: No description for 3dlbA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle