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View Structure Prediction Details

Protein: alp-1
Organism: Caenorhabditis elegans
Length: 771 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for alp-1.

Description E-value Query
Range
Subject
Range
gi|73970462 - gi|73970462|ref|XP_531880.2| PREDICTED: similar to Zinc finger protein 208 [Canis familiaris]
684.0 [0..102] [770..341]

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Predicted Domain #1
Region A:
Residues: [1-97]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVRITTTPRP WQPSGAATRI WRPEVTENTG PGQDQTPYRV NLQHSSDTRP PQGFNNSALP  60
   61 FETDQRVKHM QYNSPLGIYS DKSAAEQYVQ QTQGLGD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [98-253]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NSGARAAAQR QDEPAYLRSE TLRLLKEQEH GSAGGAGTTL SNHPNPSGLP VCFMCTRPIL  60
   61 GVMARAAGKN LHGDCLSCAT CGNSLRNVGH HFIEDKFYCD IHGTQRKHGG RPGMDPNIFV 120
  121 KSSPTAAQPV HIQDSPRAAY HPQVNTARPV SVSPAP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.0
Match: 2darA
Description: No description for 2darA was found.

Predicted functions:

Term Confidence Notes
binding 2.12572817427544 bayes_pls_golite062009
protein binding 1.29473277650963 bayes_pls_golite062009
receptor activity 1.14136291123774 bayes_pls_golite062009
transporter activity 0.883869495141753 bayes_pls_golite062009
signal transducer activity 0.805976257280115 bayes_pls_golite062009
molecular transducer activity 0.805976257280115 bayes_pls_golite062009
transmembrane transporter activity 0.69816175939074 bayes_pls_golite062009
DNA binding 0.553317759726036 bayes_pls_golite062009
substrate-specific transporter activity 0.480921069521595 bayes_pls_golite062009
nucleic acid binding 0.421612378286018 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.248246733554633 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [254-387]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SAGSKTVTTH YHTPKTQGIL SPGQRGVPTA AFGADLSKSV TYGGGVGPGG THYDSNRLSP  60
   61 APSQYSTQSR NQSQQHYQQH VVQAPPPVPS NPPPSNGLRE MEDDDRVRAI ECIARHQSEL 120
  121 EQTQTQLSTL LESA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [388-679]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IVYLQNLRPE LELTEPIDND AKSLETVKFE PTRAEQRVNE IRKKVLEDLE HLPILGDGMD  60
   61 SVPPPPPERK VFPFQSYQPI APQFPVPAAE SPVTQSLHDV LDEFYSLRKP TPTQNVAQSS 120
  121 DTTAEDSRNF LASRLGQVMI DENKKAGGSN GSSQHHNQQG SSYTKTSFER TTTETRPQQN 180
  181 TGAPRAGDFR GTGHLTTTTT TQQNGGRAPF CESCKQQIRG AFVLATGKSW CPEHFVCANS 240
  241 SCRRRLLECG FVEEDGQKFC ESCFEQHIAP RCNKCSKPII SDCLNALQKK WH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 43.39794
Match: 2i13A
Description: No description for 2i13A was found.

Predicted Domain #5
Region A:
Residues: [680-771]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PTCFTCAHCQ KPFGNSAFYL EQGLPYCEQD WNALFTTKCV SCRYPIEAGD RWVEALGNAF  60
   61 HSNCFTCARC NHNLEGESFF AKNGQPFCRL HA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.154902
Match: 1meyC
Description: Designed zinc finger protein
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle