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View Structure Prediction Details

Protein: nhr-112
Organism: Caenorhabditis elegans
Length: 308 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nhr-112.

Description E-value Query
Range
Subject
Range
gi|68396885 - gi|68396885|ref|XP_683221.1| PREDICTED: similar to retinoid X receptor-alpha [Danio rerio]
219.0 [0..2] [306..242]

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Predicted Domain #1
Region A:
Residues: [1-308]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSLRCIFPQ ILSLEKARLK MIRKCYEAGM TPEKIQLTRD KHLNRTIKLE GPCSSLDTPI  60
   61 TSRQTPNLYC VLSNWHELKM TREEMNSGSL NNCNIFELTS FVLRDLELTW RMVSKAFPTV 120
  121 EVLEDRDRQA LLRNFVPKLW QIEPILEYRE CAEKFDNLEE EDYENLLVGF YGGTFPEGKE 180
  181 MSKSEIVSNF RPYWDYYYTK MILPISSMGL EELEYMAIVW LAFFDNGYSN ISDNCLEMCR 240
  241 DIQKVILKEL RNYQIDRNFH ENRFFVALEA LQIIERGEKK FMEEMLVCEM NHIRIHDDFR 300
  301 KIIREPKL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 40.39794
Match: 1lbdA
Description: LIGAND-BINDING DOMAIN OF THE HUMAN NUCLEAR RECEPTOR RXR-ALPHA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.15996699473685 bayes_pls_golite062009
transcription regulator activity 0.46162010671465 bayes_pls_golite062009
protein binding 0.33427459029264 bayes_pls_golite062009
nucleic acid binding 0.15459949087509 bayes_pls_golite062009
DNA binding 0.14395376162921 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle