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View Structure Prediction Details

Protein: CE35373
Organism: Caenorhabditis elegans
Length: 515 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE35373.

Description E-value Query
Range
Subject
Range
gi|114554492 - gi|114554492|ref|XP_001162732.1| PREDICTED: endothelin converting enzyme 1 isoform 8 [Pan troglodyte...
457.0 [0..48] [499..293]

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Predicted Domain #1
Region A:
Residues: [1-515]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKALLPFFIF SVFILFCTSK ASLPKNIIQE HIKKHADFSV DPCVDFYAHV CPWKVERYFM  60
   61 EDLSKLKAGM VAKYRKKHPK FDKFKGEDAF AIAEALKQLN IEQLKSECKP SKPRLSSFFI 120
  121 SAQDNRTIEN VDEVLFPGFE NYPCEEKAAI IIKEVGEIED YTTTRSVLVS AVNGFITSKL 180
  181 VEKLDVKARK LFNKFKSVIS KEIIKTPWAK NYKAIEQYVE ALSNITFRTF ADVRITVKKS 240
  241 MELYESTEKD CRKKLDVAFS QPTAELVCKG VATRKAEELL DEPIEDIFPQ DQAGILKDVW 300
  301 QMFNSFDNSV YIGNEFLLLL NTDYFSDLYG SIGFSMIHEI MHTLVFDDND LDKPLSKLWT 360
  361 KNADCVKDQA LKTCETFPTV TEMHNMKPAC NTTVTFEEDA ADLAAYRIAW RIYENSYARK 420
  421 TVVPNYEALD KKQLFFYGAA VFFCNQDGMS RVPFQNLAHS NNYQRVNSLM SQMKQFSDAF 480
  481 KCKPTDKMIT NRAKHCELYG SGSPMTRKKN AGNYY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 110.0
Match: 1dmtA
Description: Neutral endopeptidase (neprilysin)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.361128926739778 bayes_pls_golite062009
hydrolase activity 0.29183147920977 bayes_pls_golite062009
peptidase activity 0.23695590197447 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 0.0341081586881899 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle