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View Structure Prediction Details

Protein: CE35350
Organism: Caenorhabditis elegans
Length: 525 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE35350.

Description E-value Query
Range
Subject
Range
gi|4406272, gi|7... - pir||T11289 cytochrome-c oxidase (EC 1.9.3.1) chain I - Raja radiata mitochondrion, gi|5836075|ref|...
gi|5836075|ref|N... - cytochrome c oxidase subunit I [Raja radiata], cytochrome c oxidase subunit I [Raja radiata]
637.0 [0..11] [521..3]

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Predicted Domain #1
Region A:
Residues: [1-525]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNLYKKYQGG LAVWLESSNH KDIGTLYFIF GLWSGMVGTS FSLLIRLELA KPGFFLSNGQ  60
   61 LYNSVITAHA ILMIFFMVMP TMIGGFGNWL LPLMLGAPDM SFPRLNNLSF WLLPTSMLLI 120
  121 LDACFVDMGC GTSWTVYPPL STMGHPGSSV DLAIFSLHAA GLSSILGGIN FMCTTKNLRS 180
  181 SSISLEHMTL FVWTVFVTVF LLVLSLPVLA GAITMLLTDR NLNTSFFDPS TGGNPLIYQH 240
  241 LFWFFGHPEV YILILPAFGI VSQSTLYLTG KKEVFGALGM VYAILSIGLI GCVVWAHHMY 300
  301 TVGMDLDSRA YFSAATMVIA VPTGVKVFSW LATLFGMKMV FNPLLLWVLG FIFLFTLGGL 360
  361 TGVVLSNSSL DIILHDTYYV VSHFHYVLSL GAVFGIFTGV TLWWSFITGY VLDKLMMSAV 420
  421 FILLFIGVNL TFFPLHFAGL HGFPRKYLDY PDVYSVWNII ASYGSIISTA GLFLFIYVLL 480
  481 ESFFSYRLVI SDYYSNSSPE YCMSNYVFGH SYQSEIYFST TSLKN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 173.0
Match: 1occA
Description: Mitochondrial cytochrome c oxidase, subunit I
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
heme-copper terminal oxidase activity 14.1725811596039 bayes_pls_golite062009
cytochrome-c oxidase activity 13.8542976951523 bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors, oxygen as acceptor 13.8542976951523 bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors 13.8542976951523 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 7.37127314407573 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 7.21569868255501 bayes_pls_golite062009
oxidoreductase activity 7.16307962729639 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 6.59819712923927 bayes_pls_golite062009
cation transmembrane transporter activity 6.32599750294462 bayes_pls_golite062009
ion transmembrane transporter activity 6.1152058837897 bayes_pls_golite062009
oxidoreductase activity, acting on diphenols and related substances as donors 5.8923420516615 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 5.6803770025358 bayes_pls_golite062009
substrate-specific transporter activity 5.45928453313406 bayes_pls_golite062009
catalytic activity 1.95966890211023 bayes_pls_golite062009
oxidoreduction-driven active transmembrane transporter activity 1.51081278400602 bayes_pls_golite062009
electron carrier activity 1.29518639068237 bayes_pls_golite062009
binding 0.89004160546195 bayes_pls_golite062009
oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor 0.531607015518545 bayes_pls_golite062009
transporter activity 0.37947088637216 bayes_pls_golite062009
transmembrane transporter activity 0.36572623683433 bayes_pls_golite062009
protein binding 0.358081002328109 bayes_pls_golite062009

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