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View Structure Prediction Details

Protein: CE35224
Organism: Caenorhabditis elegans
Length: 397 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE35224.

Description E-value Query
Range
Subject
Range
gi|13384746, gi|... - gi|13384746|ref|NP_079647.1| aminoacylase 1 [Mus musculus], gi|12834533|dbj|BAB22948.1| unnamed prot...
310.0 [0..2] [396..8]

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Predicted Domain #1
Region A:
Residues: [1-178]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEDIGVTRF REYLRVNTEQ PKPDYEACRD FLFKYADELG IERRSVETAP GTYFVIMTIP  60
   61 GSKPDLPSIM LYSHTDVVPT FREYWTHDPY SAFKDEDGNI FARGAQDMKC VGVQYMEALR 120
  121 NWFAKGVKQW TRTIHIVWGP DEEIGHINGM KGFAVTEEFK KLNIDFALDE GIATEDDV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 36.09691
Match: 1q7lA
Description: Zn-binding domain of the T347G mutant of human aminoacylase-I
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [179-310]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YKIFYAERIP WWVKVTLPGH PGHGSKFIEK TAIEKLHKLI ASVDEFRNEQ KSLLAEHPEW  60
   61 TVGDVTTSNI TIINGGVQVN VVPEKFEAYI DIRVTPLQDL DAVLARVDQW AKEAGEGVTY 120
  121 EFMQFSNFKL IS

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.0
Match: 1ysjA
Description: Crystal Structure of Bacillus Subtilis YXEP Protein (APC1829), a Dinuclear Metal Binding Peptidase from M20 Family
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 3.2460337099697 bayes_pls_golite062009
hydrolase activity 2.89801951009786 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 2.58805472741431 bayes_pls_golite062009
catalytic activity 1.84228605319441 bayes_pls_golite062009
exopeptidase activity 0.574424638244179 bayes_pls_golite062009
binding 0.477837256878116 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [311-397]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNTREDPFWA AIDDALQKEG CKYKKEIFIG ATDSRFVRAQ GIRAIGFSPI INTPSLLHDH  60
   61 NEFLNEKTFL RGVEIYETLI NKLANVN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10.522879
Match: 1q7lB
Description: Zn-binding domain of the T347G mutant of human aminoacylase-I
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle