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View Structure Prediction Details

Protein: npp-10
Organism: Caenorhabditis elegans
Length: 492 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for npp-10.

Description E-value Query
Range
Subject
Range
npp-10 - nucleoporin \; DNA-directed RNA polymerase status:Partially_confirmed UniProt:Q23464 protein_id:AAP6...
460.0 [0..1] [492..1]

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Predicted Domain #1
Region A:
Residues: [1-156]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQQQVAPVPV IGVTADVLQM QANMKSLKSQ LTNAPYGDSP LLKYNANPEI DGKSSPASTQ  60
   61 RQLRFLAAKK GALSSSSDAQ DSSFIIPPIS KVMSDLSPAV TRSADVTKDL NYTSKEAPPS 120
  121 LARGLRNSTF NPNMSLTNRS VHESSALDKT IDSALD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [157-265]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASMNGTSNRL GVRGSVRRSN LKQLDMSLLA DSSRVGRESR VADPDALPRI SESERRQDVV  60
   61 TSTPAVDPVQ AVIQRHNDRN RDPPSLNLDT TCDEHTGLEP VSAATSSAA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [266-492]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SVVSTPSEET VNVNSAAGVK LTKPDYFSLP TINEMKNMIK NGRVVLEDGL TVGRSSYGSV  60
   61 YWPGRVELKD VALDEIVVFR HREVTVYPNE EEKAPEGQEL NRPAEVTLER VWYTDKKTKK 120
  121 EVRDVVKLSE IGWREHLERQ TIRMGAAFKD FRAETGSWVF RVDHFSKYGL ADDDEPMDGS 180
  181 PPQQALQASS PLQVIDMNTS ARDVNNQVQR KKVHKATDAH HQEVRFE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 68.0
Match: 1ko6A
Description: C-terminal autoproteolytic domain of nucleoporin nup98
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle