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View Structure Prediction Details

Protein: pyp-1
Organism: Caenorhabditis elegans
Length: 338 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pyp-1.

Description E-value Query
Range
Subject
Range
pyp-1 - inorganic pyrophosphatase status:Confirmed UniProt:Q18680 protein_id:CAA93107.3
404.0 [0..26] [338..94]

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Predicted Domain #1
Region A:
Residues: [1-338]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGLVLIAKRN KPLIAMMAAI LFTVAVFLAT RPLSETAVIL QSQAVKMSTG AGDSAVYEAV  60
   61 ERGSLYSLDY RVYIKGPQGI VSPWHDIPLF ANKDKRVYNM IVEIPRWTNA KMEMATKEPF 120
  121 SPIKQDEKKG VARFVHNIFP HKGYIWNYGA LPQTWEDPNH VVPDTGAKGD NDPIDVIEVG 180
  181 SKVAGRGAVL QVKVLGTLAL IDEGETDWKL VAIDVNDENA DKLNDIDDVE KVYPGLLAAS 240
  241 VEWFRNYKIP AGKPANEFAF NGEFKNREYA EKVIDETNEY WKTLIKEANP SLNTVSRVPE 300
  301 AVHQGTDEAA ATAIGATPEH GANAPLPGDV DKWHFVQG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 98.221849
Match: 1m38A
Description: Inorganic pyrophosphatase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
inorganic diphosphatase activity 2.74116819406619 bayes_pls_golite062009
binding 1.77492613217844 bayes_pls_golite062009
catalytic activity 1.33262120571864 bayes_pls_golite062009
protein binding 0.38607803003281 bayes_pls_golite062009
pyrophosphatase activity 0.354425639853757 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.334860448536013 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.333575715544697 bayes_pls_golite062009
hydrolase activity 0.0110854177718558 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle