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View Structure Prediction Details

Protein: unc-78
Organism: Caenorhabditis elegans
Length: 517 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for unc-78.

Description E-value Query
Range
Subject
Range
gi|186464325, gi... - gi|23128981|ref|ZP_00110817.1| COG2319: FOG: WD40 repeat [Nostoc punctiforme PCC 73102], gi|18668187...
597.0 [0..1] [516..1198]

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Predicted Domain #1
Region A:
Residues: [1-517]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEFSQTALF PSLPRTARGT AVVLGNTPAG DKIQYCNGTS VYTVPVGSLT DTEIYTEHSH  60
   61 QTTVAKTSPS GYYCASGDVH GNVRIWDTTQ TTHILKTTIP VFSGPVKDIS WDSESKRIAA 120
  121 VGEGRERFGH VFLFDTGTSN GNLTGQARAM NSVDFKPSRP FRIISGSDDN TVAIFEGPPF 180
  181 KFKSTFGEHT KFVHSVRYNP DGSLFASTGG DGTIVLYNGV DGTKTGVFED DSLKNVAHSG 240
  241 SVFGLTWSPD GTKIASASAD KTIKIWNVAT LKVEKTIPVG TRIEDQQLGI IWTKQALVSI 300
  301 SANGFINFVN PELGSIDQVR YGHNKAITAL SSSADGKTLF SADAEGHINS WDISTGISNR 360
  361 VFPDVHATMI TGIKTTSKGD LFTVSWDDHL KVVPAGGSGV DSSKAVANKL SSQPLGLAVS 420
  421 ADGDIAVAAC YKHIAIYSHG KLTEVPISYN SSCVALSNDK QFVAVGGQDS KVHVYKLSGA 480
  481 SVSEVKTIVH PAEITSVAFS NNGAFLVATD QSRKVSF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 87.69897
Match: 1nr0A
Description: Actin interacting protein 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
actin binding 3.86142918698875 bayes_pls_golite062009
cytoskeletal protein binding 3.1056443224755 bayes_pls_golite062009
binding 2.2778252170547 bayes_pls_golite062009
actin filament binding 2.0735069176589 bayes_pls_golite062009
protein binding 1.42618832381942 bayes_pls_golite062009
myosin heavy chain kinase activity 1.24520283111044 bayes_pls_golite062009
transporter activity 1.21549336905926 bayes_pls_golite062009
myosin binding 0.989691178611801 bayes_pls_golite062009
tubulin binding 0.968047176592527 bayes_pls_golite062009
microtubule binding 0.834073483714259 bayes_pls_golite062009
substrate-specific transporter activity 0.734793983890004 bayes_pls_golite062009
dynein binding 0.41765917405931 bayes_pls_golite062009
receptor binding 0.364508343879101 bayes_pls_golite062009
0.13154833491231 bayes_pls_golite062009
structural constituent of cytoskeleton 0.118975415284669 bayes_pls_golite062009
transcription factor binding 0.0250316290871848 bayes_pls_golite062009
myosin II binding 0.0145748031956598 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle