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View Structure Prediction Details

Protein: feh-1
Organism: Caenorhabditis elegans
Length: 640 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for feh-1.

Description E-value Query
Range
Subject
Range
gi|51494725 - gi|51494725|gb|AAH27946.2| Amyloid beta (A4) precursor protein-binding, family B, member 2 [Homo sap...
528.0 [0..55] [637..104]

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Predicted Domain #1
Region A:
Residues: [1-88]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MREGTPRVRI EVNKGSNRPS QFVSESEEQR LQRVQSRDSD TATMNFVTDD RMMEEHDEYS  60
   61 AFKEAYEEEE SREYVIENGV KRLVNQHY

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [89-221]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSRGYSSAGR GQKGRREEER RRNMAVDYSS QDFRQSLAAI DQASRDGAIS RGEDGVRVRQ  60
   61 IGDTTIMTEH RDPYSFYWQL DQARREAESP PRRPPPTDYV IDEEEEVLET VYSPEADDVM 120
  121 FENQYRRPVR HPL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [222-334]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPPPPIMEEE PKDLPPGWEK HEDPQGYSYY WHVDSGTIQR QPPPPVNRET QADAPPPQII  60
   61 QLPPQQPVIE EHAFKQTTTK RRIEQDEMSE REIEDVAMIE NGDTYHKPVR FAV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10.221849
Match: 2f21A
Description: No description for 2f21A was found.

Predicted Domain #4
Region A:
Residues: [335-376]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RSLGWTDISE DELTAEKSSR AVNRAIVDLT TRSDIDSIPK WG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.09691
Match: 2dk7A
Description: No description for 2dk7A was found.

Predicted Domain #5
Region A:
Residues: [377-481]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DGRELIMELD DNELALLDPD SMNVIHSERI QAIRVWGVGR DNGRDFAYVS RDRGTRRFMC  60
   61 HVFRCDTSAK TIANTLRDIC KRLMLHRRPS SLHAIESGEK RIVRS

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.72
Match: 1m7eA
Description: Crystal structure of the phosphotyrosine binding domain(PTB) of mouse Disabled 2(Dab2):implications for Reeling signaling
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [482-640]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EGLTAPIDEP RKVIRCHFLG VTQVPKATGI EILNEAVDRL VSQVRSERWI LADVSIAPST  60
   61 IAIVEVNGQQ IAECRVRYLS FLGIGRDVKH CAFIMQTSSE SFMCYVFHVE PNAAAMAKMV 120
  121 EAACKLRYQK VLDAHSSSRH HSGMSIHGQH PPSTYHGMD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 44.522879
Match: 1wguA
Description: Solution Structure of the C-terminal Phosphotyrosine Interaction Domain of APBB2 from Mouse
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle