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View Structure Prediction Details

Protein: feh-1
Organism: Caenorhabditis elegans
Length: 640 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for feh-1.

Description E-value Query
Range
Subject
Range
gi|51494725 - gi|51494725|gb|AAH27946.2| Amyloid beta (A4) precursor protein-binding, family B, member 2 [Homo sap...
528.0 [0..55] [637..104]

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Predicted Domain #1
Region A:
Residues: [1-88]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MREGTPRVRI EVNKGSNRPS QFVSESEEQR LQRVQSRDSD TATMNFVTDD RMMEEHDEYS  60
   61 AFKEAYEEEE SREYVIENGV KRLVNQHY

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [89-221]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSRGYSSAGR GQKGRREEER RRNMAVDYSS QDFRQSLAAI DQASRDGAIS RGEDGVRVRQ  60
   61 IGDTTIMTEH RDPYSFYWQL DQARREAESP PRRPPPTDYV IDEEEEVLET VYSPEADDVM 120
  121 FENQYRRPVR HPL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [222-334]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPPPPIMEEE PKDLPPGWEK HEDPQGYSYY WHVDSGTIQR QPPPPVNRET QADAPPPQII  60
   61 QLPPQQPVIE EHAFKQTTTK RRIEQDEMSE REIEDVAMIE NGDTYHKPVR FAV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10.221849
Match: 2f21A
Description: No description for 2f21A was found.

Predicted Domain #4
Region A:
Residues: [335-376]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RSLGWTDISE DELTAEKSSR AVNRAIVDLT TRSDIDSIPK WG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.09691
Match: 2dk7A
Description: No description for 2dk7A was found.

Predicted Domain #5
Region A:
Residues: [377-481]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DGRELIMELD DNELALLDPD SMNVIHSERI QAIRVWGVGR DNGRDFAYVS RDRGTRRFMC  60
   61 HVFRCDTSAK TIANTLRDIC KRLMLHRRPS SLHAIESGEK RIVRS

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.72
Match: 1m7eA
Description: Crystal structure of the phosphotyrosine binding domain(PTB) of mouse Disabled 2(Dab2):implications for Reeling signaling
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [482-640]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EGLTAPIDEP RKVIRCHFLG VTQVPKATGI EILNEAVDRL VSQVRSERWI LADVSIAPST  60
   61 IAIVEVNGQQ IAECRVRYLS FLGIGRDVKH CAFIMQTSSE SFMCYVFHVE PNAAAMAKMV 120
  121 EAACKLRYQK VLDAHSSSRH HSGMSIHGQH PPSTYHGMD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 44.522879
Match: 1wguA
Description: Solution Structure of the C-terminal Phosphotyrosine Interaction Domain of APBB2 from Mouse
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle