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View Structure Prediction Details

Protein: shk-1
Organism: Caenorhabditis elegans
Length: 536 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for shk-1.

Description E-value Query
Range
Subject
Range
shk-1 - status:Partially_confirmed UniProt:Q8I4B1 protein_id:CAD57715.1
330.0 [0..1] [536..1]

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Predicted Domain #1
Region A:
Residues: [1-90]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRFGGQRRCI ESSDDNDSID SMSIQQKNKE KEEWKWAQSL ARRLEQVLNV HPEKYQNGCS  60
   61 SQRPSRQPSP VEQLAPIRSH SADFGRAAEM 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [91-536]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASGNSEEGKG MLLRNGDDRI RLPSPQRGTP DTSSTQGHPY TDQIVTINVS GMRFQTFEST  60
   61 LSRYPNSLLG DRNKRQHFFV SDTNEFFFDR HRTTSSSFTF EIRNYLFESI LYIYQSGGRV 120
  121 KRPEIVPIDI FLKEMRFFQM GDDLLEEFWI AEGYEKPKEV MMPNNKTQRK IWELMEYPDS 180
  181 SLSARIIAFI SIAVIALSII SFCWETVPSD IEEKPINNSA TAELLDEMDE KHYSPFFWIE 240
  241 LMCILWFTIE LILRFISCPC KVTFATSVLN IIDFVAIAPF FVNFFFADTS KSNSSMSFAV 300
  301 LRVLRLVRVF RVFKLSRHSV GLQILGKTFR SSVQEFCLLI FFMAIALVLF ASGMYFAEQG 360
  361 EPNSKFTSIP ASFWFVLVTM TTVGYGDLVP LSPFGKVVGG MCAMIGVLTL ALPVPIIVAN 420
  421 FKHFYRQENR LASMKSKGDD ADDDIA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 83.221849
Match: 2a79B
Description: Mammalian Shaker Kv1.2 potassium channel- beta subunit complex
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle