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View Structure Prediction Details

Protein: wsp-1
Organism: Caenorhabditis elegans
Length: 607 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for wsp-1.

Description E-value Query
Range
Subject
Range
gi|149065100, gi... - gi|160333510|ref|NP_001103835.1| Wiskott-Aldrich syndrome-like [Rattus norvegicus], gi|149065100|gb|...
273.0 [0..12] [333..1]

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Predicted Domain #1
Region A:
Residues: [1-165]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVYPPTPTM SMMNGGVDRK RAKRPPNVGS KELNSQENEM LFALVGSEAV CLTAAVVQLL  60
   61 KSDRGAWRVD LPHGVISLVK DYAQRAYFLR IFDILEERIV WDFKLYKAFR AQSFPQCRKL 120
  121 LAFEQMENGE DGVVIGLNFF SEYEAAEFKE HLERRHAQER KSTST

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 56.221849
Match: 1mkeA
Description: Actin regulatory protein WASP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.597587183571285 bayes_pls_golite062009
protein binding 0.29116370406325 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [166-235]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TRPAHPGMPI VVSSGIGSTP TRQFEITQAY GGTIRGPPMA IGGGQGITQM GTMAAAPQSH  60
   61 THTDGNASSS 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [236-349]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSWFRKDKNK KKDKKSKIKK EDISNPTNFQ HKAHVGWNQD SGFSNTVYDD DMDEATKNIL  60
   61 KAAGLESNNL NEDDKKFVKK FIAKNYDKYV SVGSLDPSQI SSPLPPPIQQ HPQM

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.03
Match: 1ej5A
Description: Wiscott-Aldrich syndrome protein, WASP, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [350-502]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NQSWNQTPVR QYKPSFPSSA PIGSGASSYS TPAAPPPPTR VESHGLAPAR PPPPPPSSGT  60
   61 RGIAPSRPLP QAPNYGTPEN RPHAVPPPPP PPPPQSFGMA PISSAAPPPP PPPPPMGLPA 120
  121 VGAGAPPPPP PPPPSGAGGP ASVLAKLPPA QDG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [503-607]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RSNLLAEIQA GKQLRSVQQT ADSPKSAGGD ARGDVMAQIR QGAQLKHVDA AAEQERRKST  60
   61 TSGAAGMGGL AGALAKALEE RRMNMGIDDT SDDDDDEDDK NEWSD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle