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View Structure Prediction Details

Protein: wsp-1
Organism: Caenorhabditis elegans
Length: 607 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for wsp-1.

Description E-value Query
Range
Subject
Range
gi|149065100, gi... - gi|160333510|ref|NP_001103835.1| Wiskott-Aldrich syndrome-like [Rattus norvegicus], gi|149065100|gb|...
273.0 [0..12] [333..1]

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Predicted Domain #1
Region A:
Residues: [1-165]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVYPPTPTM SMMNGGVDRK RAKRPPNVGS KELNSQENEM LFALVGSEAV CLTAAVVQLL  60
   61 KSDRGAWRVD LPHGVISLVK DYAQRAYFLR IFDILEERIV WDFKLYKAFR AQSFPQCRKL 120
  121 LAFEQMENGE DGVVIGLNFF SEYEAAEFKE HLERRHAQER KSTST

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 56.221849
Match: 1mkeA
Description: Actin regulatory protein WASP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.597587183571285 bayes_pls_golite062009
protein binding 0.29116370406325 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [166-235]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TRPAHPGMPI VVSSGIGSTP TRQFEITQAY GGTIRGPPMA IGGGQGITQM GTMAAAPQSH  60
   61 THTDGNASSS 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [236-349]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSWFRKDKNK KKDKKSKIKK EDISNPTNFQ HKAHVGWNQD SGFSNTVYDD DMDEATKNIL  60
   61 KAAGLESNNL NEDDKKFVKK FIAKNYDKYV SVGSLDPSQI SSPLPPPIQQ HPQM

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.03
Match: 1ej5A
Description: Wiscott-Aldrich syndrome protein, WASP, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [350-502]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NQSWNQTPVR QYKPSFPSSA PIGSGASSYS TPAAPPPPTR VESHGLAPAR PPPPPPSSGT  60
   61 RGIAPSRPLP QAPNYGTPEN RPHAVPPPPP PPPPQSFGMA PISSAAPPPP PPPPPMGLPA 120
  121 VGAGAPPPPP PPPPSGAGGP ASVLAKLPPA QDG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [503-607]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RSNLLAEIQA GKQLRSVQQT ADSPKSAGGD ARGDVMAQIR QGAQLKHVDA AAEQERRKST  60
   61 TSGAAGMGGL AGALAKALEE RRMNMGIDDT SDDDDDEDDK NEWSD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle