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View Structure Prediction Details

Protein: lst-4
Organism: Caenorhabditis elegans
Length: 592 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for lst-4.

Description E-value Query
Range
Subject
Range
gi|109077219 - gi|109077219|ref|XP_001096681.1| PREDICTED: similar to sorting nexin associated golgi protein 1 [Mac...
370.0 [0..24] [592..45]

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Predicted Domain #1
Region A:
Residues: [1-185]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLFTSSLRKA VENYPTPPGG SSEDAHRQLL ERRRKQMLRR HTCSTLIKQD TSASPHKMKP  60
   61 PILMEEEDEQ HSTGKHSSRK SSFKKSGAIS KSVLPPPLPP TSSGPPAASS RPFDDWGGAS 120
  121 EVAAPPSYGA QHHHQPTPSV PEVTRSSYPS QNDDFDDEWT DEDDEQEPTR PNVQSSIGSN 180
  181 SRRDL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [186-251]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SRSHSEHGGP DRGSNKVNKN INRFSNFVKS GVEAYVIGES KTTSQISERH EVVMNNGIIQ  60
   61 WKPIQQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [252-528]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YYTCIVDKPK KESKLKGLKS FIAYSITSSL TNIQRQVSRR YKHFDWLHEQ LSAKYVLIPI  60
   61 PPLPEKQVAG RYEEDLIDHR KHILQLWVNK ICRHPVLSQS EVWLHFISCT DEKDWKNGKR 120
  121 RAEKDEYIGG AFLNCITVPH QPLDPNNVDM QVERFQRSVK TSEEAMRVMQ ERMNMFQKVF 180
  181 AGPVKQNWQK MGSAFKTLQQ SFEIDETVAS RRLTEALAYT ASEYHEIGQV FDAHTKNDME 240
  241 PVLENLYSYK GTVQNVPDII QVHKQAVQKF RDSEGRL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.522879
Match: 2dybA
Description: No description for 2dybA was found.

Predicted Domain #4
Region A:
Residues: [529-592]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSAEAEKMKQ RIDAMSYTVI AEVQHQTAEK VEDMKSTMGT YLKKQAMFYQ EVATKLTSLA  60
   61 ARYD

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.15
Match: 1uruA
Description: Amphiphysin BAR domain from Drosophila
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle