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View Structure Prediction Details

Protein: pde-4
Organism: Caenorhabditis elegans
Length: 599 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pde-4.

Description E-value Query
Range
Subject
Range
gi|73956336 - gi|73956336|ref|XP_536678.2| PREDICTED: similar to phosphodiesterase 4B, cAMP-specific (phosphodiest...
647.0 [0..9] [596..68]

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Predicted Domain #1
Region A:
Residues: [1-126]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSRRHTVWF VPGSRSAGSA TAADGLGGAH LTPSLSSSVH ARRESFLYRA SDDLREASSL  60
   61 RPVSRASSIA SNEHGHGDDL IVTPFAQLLA SLRNVRSNLI SITNIQNSDD SRHANRSAKR 120
  121 PPLHNI

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [127-250]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ELPDDVVHCA HDTLEELDWC LDQLETIQTH RSVSEMASSK FRKMLNKELS HFAESSKSGT  60
   61 QVSKFLITTY MDKEEDEPSI EIEVPTEVQG PSTSGPMTLS ILKKAQTAAM NKISGVRKLR 120
  121 APSH

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [251-599]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DGHVPEYGVN CAREIAVHMQ RLDDWGPDVF KIDELSKNHS LTVVTFSLLR QRNLFKTFEI  60
   61 HQSTLVTYLL NLEHHYRNNH YHNFIHAADV AQSMHVLLMS PVLTEVFTDL EVLAAIFAGA 120
  121 VHDVDHPGFT NQYLINSNNE LAIMYNDESV LEQHHLAVAF KLLQDSNCDF LANLSRKQRL 180
  181 QFRKIVIDMV LATDMSKHMS LLADLKTMVE AKKVAGNNVI VLDKYNDKIQ VLQSMIHLAD 240
  241 LSNPTKPIEL YQQWNQRIME EYWRQGDKEK ELGLEISPMC DRGNVTIEKS QVGFIDYIVH 300
  301 PLYETWADLV YPDAQNILDQ LEENREWYQS RIPEEPDTAR TVTEDDEHK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 122.0
Match: 1oynA
Description: Catalytic domain of cyclic nucleotide phosphodiesterase pde4d
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle