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View Structure Prediction Details

Protein: pbo-5
Organism: Caenorhabditis elegans
Length: 504 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pbo-5.

Description E-value Query
Range
Subject
Range
gi|73974924 - gi|73974924|ref|XP_539232.2| PREDICTED: similar to cholinergic receptor, nicotinic, alpha polypeptid...
382.0 [0..61] [503..99]

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Predicted Domain #1
Region A:
Residues: [1-368]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTRLSILQHL LTFLILSKIN ATSTTESYFD SSEEAPNVLL NHLNNESEGE ELTQINDTQP  60
   61 AFVPGSSKRL TEYLLSRHNL NAPPDGLLYV EYELELVHIL GIDELKQTMT VLIYVDEHWV 120
  121 DPSLTWDPAL FGGITKTWIP LDKIWVPDII VFNMLAHEDL LSAVRAPARI HYNGTIVASH 180
  181 PAVHTVSCEI NIRHFPLDDQ RCAIEIASWA YGQEKIRLHA HTDHSLEHYK RNEEWHLLNL 240
  241 NVSEEKYEHE GVEVSEVKFE ISLKRRPLFY MVTLTFPSYI MCAISVVGLF ARFSTTGERE 300
  301 ERFTLGVTAI LTMAVLSLVV SEKVPHSSTH VPLLVAYFLF NMVIVSIAAM TTGIVMKVHR 360
  361 LGRYGDEP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 72.221849
Match: 2bg9A
Description: Refined structure of the nicotinic acetylcholine receptor at 4A resolution.
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [369-504]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SDFWMRCFLL KPVFRTSNRR KYRMNPEEPT QVILVSEAKN GEVLTKKSTE LNGTVVKEIM  60
   61 LSSRLEALEE YIRKMVNRCE TIKWELDEID AAENIELVRR RSTNGYVRIS ERLDILFMFL 120
  121 FLSTVTIPVA VLFYLT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 38.522879
Match: 1oedB
Description: Acetylcholine receptor protein, beta chain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
beta-amyloid binding 2.54213155474327 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle