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View Structure Prediction Details

Protein: apt-9
Organism: Caenorhabditis elegans
Length: 588 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for apt-9.

Description E-value Query
Range
Subject
Range
GGA1 - golgi-associated, gamma adaptin ear containing, ARF binding protein 1
385.0 [0..2] [584..3]

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Predicted Domain #1
Region A:
Residues: [1-147]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEEEPVRPID YWVCRATDRF IGDEERIKAL DFIIESIYKQ PASALLAVDL FSHKLSSPSQ  60
   61 EEAMLTIRAL DYLVRNGGEK VHERCGRYKF LNELVRLIAP KYNGKLTSDA LKTEIIKLLF 120
  121 IWQLSIKHIP KYKQVYESLK LSKIITD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 51.30103
Match: 1jplA
Description: ADP-ribosylation factor binding protein Gga3
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein binding 1.44619623515316 bayes_pls_golite062009
binding 1.13238817008904 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [148-324]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPHVRETEVP VFAVPPVRSS VFDNEEQAVL LKALLSSNRP EDLETANNLI KTLVETEEHK  60
   61 LVKIHERRKK LDHAINLCNQ VEHLRLDKAA ETIGLGNYSP DNELTLQRVT NELIQLQELF 120
  121 YGYVNELAEN NDPCLEEVLN INDQINRVLP ENETPKCGNR APISARTQLD PENQELL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.0
Match: 1oxzA
Description: ADP-ribosylation factor binding protein Gga1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein binding 1.23852637357121 bayes_pls_golite062009
clathrin binding 1.10771940280602 bayes_pls_golite062009
binding 1.00165323191449 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [325-397]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VFNTPTSEVP PKNGFCDPRD LEGSLLNNMI ESEFVEEPKI VPVQQMTPVL NRNSSASPRA  60
   61 SGDSSIFETD FLA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [398-588]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKRLPEPLKP PTLNELKPNT TTITLEALEV LVPPMSPEPT SLSPKAIPEK VALNPSSIIM  60
   61 RNRVPIEVLY SKGMRILLYY CQSDMTVSNI HSYVLVIQNH NNFTIKDVNL SLKTNDKNVI 120
  121 IRLQDSVNNL AGFNIFGQQE TINLLLCIQQ LNDVKDVELD FTLAYKKSLE SAISGSFTLP 180
  181 IIPEHIFNIN F

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.69897
Match: 1p4uA
Description: ADP-ribosylation factor binding protein Gga3 domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein binding 0.859533416004855 bayes_pls_golite062009
binding 0.575039289605127 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle