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View Structure Prediction Details

Protein: alh-11
Organism: Caenorhabditis elegans
Length: 503 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for alh-11.

Description E-value Query
Range
Subject
Range
gi|52785994, gi|... - gi|52785994|ref|YP_091823.1| DhaS [Bacillus licheniformis ATCC 14580], gi|52348496|gb|AAU41130.1| Dh...
615.0 [0..2] [498..3]

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Predicted Domain #1
Region A:
Residues: [1-503]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRIFPNLINL NSLTETKLLE LSSHFVAGNH VEFPSDRKFE VIEPRSGKPM ATWHYATRDQ  60
   61 VDLTVKEAKK AQKQWAKSSW MERSEILKKT GDLLKTHCND IAYWECISNG KPIAEAKADV 120
  121 LSCVDTFYFY SGIASDLLGQ HVPLDASRYA YTRRLPVGVV AAIGAWNYPI QTCSWKTAPA 180
  181 LACGNAVIYK PSPLSPVTAL ILAEILKSAG LPDGVFNVIQ GDAETAQDLI HHDGVSKVSF 240
  241 TGSIPTGKKI MKACADRNIK PVTLELGGKS ALIVFDDADI DSAVSCAMMA NFYSQGQVCS 300
  301 NASKVLVHKS VLKEFTKKLV DHTQKMKIGD PLKEDTQVGS HISAEHRNKV EGYISTAIAE 360
  361 GATKLCGGDR VAVHGLENGF YLSPCILTGI TPKMTVYREE IFGSVLLIIP FDTEDEAIKI 420
  421 ANDTDMGLAA GLVTKDLSRS YRVSEQLNAG NVYVNTYNDV SPLVPFGGVG ESGFGRENGT 480
  481 AVLEHYTHLK SVFVNTGTCP NPF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 155.0
Match: 1a4sA
Description: Aldehyde reductase (dehydrogenase), ALDH
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
oxidoreductase activity, acting on the aldehyde or oxo group of donors 5.09598561374689 bayes_pls_golite062009
oxidoreductase activity 4.47226217021998 bayes_pls_golite062009
1-pyrroline-5-carboxylate dehydrogenase activity 4.35175408702761 bayes_pls_golite062009
malonate-semialdehyde dehydrogenase (acetylating) activity 4.2273960318884 bayes_pls_golite062009
methylmalonate-semialdehyde dehydrogenase (acylating) activity 3.87605237828483 bayes_pls_golite062009
succinate-semialdehyde dehydrogenase [NAD(P)+] activity 3.64672165191647 bayes_pls_golite062009
3-chloroallyl aldehyde dehydrogenase activity 3.37049090049734 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 3.2867555127991 bayes_pls_golite062009
glutamate-5-semialdehyde dehydrogenase activity 3.27180265380824 bayes_pls_golite062009
benzaldehyde dehydrogenase activity 2.99564252244797 bayes_pls_golite062009
aldehyde dehydrogenase (NAD) activity 2.81851373615334 bayes_pls_golite062009
catalytic activity 2.80804701752928 bayes_pls_golite062009
succinate-semialdehyde dehydrogenase activity 2.71501590413507 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH group of donors 2.70230501280821 bayes_pls_golite062009
aldehyde dehydrogenase [NAD(P)+] activity 2.43250909158896 bayes_pls_golite062009
aminobutyraldehyde dehydrogenase activity 2.35958138496479 bayes_pls_golite062009
acyl-CoA binding 2.26220696569489 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 1.6559690223037 bayes_pls_golite062009
retinal dehydrogenase activity 1.42867174920845 bayes_pls_golite062009
binding 1.06673666884196 bayes_pls_golite062009
protein binding 0.894945263794726 bayes_pls_golite062009
retinoid binding 0.801468424891608 bayes_pls_golite062009
isoprenoid binding 0.719034630339067 bayes_pls_golite062009
histidinol dehydrogenase activity 0.258030369394064 bayes_pls_golite062009
benzaldehyde dehydrogenase (NAD+) activity 0.23487570676521 bayes_pls_golite062009

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