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View Structure Prediction Details

Protein: nhr-117
Organism: Caenorhabditis elegans
Length: 477 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nhr-117.

Description E-value Query
Range
Subject
Range
gi|73967652 - gi|73967652|ref|XP_548399.2| PREDICTED: similar to Retinoic acid receptor RXR-alpha (Retinoid X rece...
276.0 [0..1] [476..23]

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Predicted Domain #1
Region A:
Residues: [1-186]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQNSIDFCSA SSSTSSNYSS PPAVLDIDQV LEKCQICYQP GHGYHFGAFI CRACAAFFRR  60
   61 CHFSLALDQR KCRLLSGSCQ PNKNGRWFCK KCRFDKCLEL GMTTTNIQYD RDAFKSSASF 120
  121 LKNKSVAKRV ADRVSVPMQF SSNQRHVIYN VKNVFQTPPT ALGKAGRTLD ETDQRILCQN 180
  181 TVESAL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 23.69897
Match: 2a66A
Description: Human Liver Receptor Homologue DNA-Binding Domain (hLRH-1 DBD) in Complex with dsDNA from the hCYP7A1 Promoter
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [187-477]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GINPIMIFTY ADENKQFPFI DISQLVDKAL SSILTPISVR KIKKMSNLEQ LTQGLDEFQW  60
   61 TQKESVSQIV RLSANDHLND FQTYMCAAAK WLSYSDRIRN LDDELKIQIL QCIWFNWGRL 120
  121 ERIATTAKMR NKRKCGKKQF VFSNNILLDY DEMSSDLSFW SNYTFEEMKY FFIPTEMFYD 180
  181 EVICEMEEVQ PDNMETTFII SLMCFHLTGK QFGGQVQEEM DQLQDLLSDE LHEYYLKKNM 240
  241 TMYSLRLKQL MKIKEKFLKL RYKRCEKYKI AGIFEAFHTN LSNPEFFMIP A

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 43.39794
Match: 2gl8A
Description: No description for 2gl8A was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle