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View Structure Prediction Details

Protein: mpk-2
Organism: Caenorhabditis elegans
Length: 605 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mpk-2.

Description E-value Query
Range
Subject
Range
mpk-2 - status:Confirmed UniProt:Q6ABN8 protein_id:AAT81209.1
417.0 [0..36] [605..1]

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Predicted Domain #1
Region A:
Residues: [1-406]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSARTTLYRA PNYYSTNIIE HKTYSISKNT VNKSKMAAPA ESHARLDGRF WLEGTPYLAE  60
   61 ENVGAGAYGV VCKAMDTRNK KQVAIKKIPR AFTAHTLAKR SLREVRILRE LLHENIIAVL 120
  121 DMFTAEGAHG KDIYLVMDLM ETDLHQILHS RQTLMEQHFQ YFFYQLLRGL KYLHSAGIIH 180
  181 RDLKPSNLLL NGDCLLRIAD FGMARAYASA STVRDDANVG GHMTQYVSTR WYRAPEILFS 240
  241 MVEYDTKVDL WSAGCIFAEM LLRRQLFPGK DSVSQIKMIV YYLGSPEEEV INRITSDLVR 300
  301 DSIEACGRKT PLPFSAIFPK ASPEARNMVS YLLQISPWKR YSADQILQHP FMAQYHNDQY 360
  361 EPLCPPRVQV DVDAIERFEG AQVVAGLDEE ARIFEMRRGT NYDTRK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 86.39794
Match: 2baqA
Description: p38alpha bound to Ro3201195
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [407-605]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPPPYLDDKS NQTFEPDKEG KMGPREDPTD YLGVIRQFQK TREQKDDDIS DSDETPTSLS  60
   61 SAETIDTVRE VELHRKCSEE NYSSDSGMEP STSNANLIVQ EIFKNGINWP LDVTSISSAP 120
  121 PMLSGGIPPS KKSKNHLDRR NIDRIREGYS EKRRFIPKIR DKRASSDSSS KLDDKDRIVR 180
  181 LRKSRQELRK TSKDDDRGV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle