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View Structure Prediction Details

Protein: CE30453
Organism: Caenorhabditis elegans
Length: 429 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE30453.

Description E-value Query
Range
Subject
Range
bca-1 - carbonic anhydrase status:Confirmed UniProt:Q22460 protein_id:AAK39291.1
264.0 [0..160] [429..1]

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Predicted Domain #1
Region A:
Residues: [1-114]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTPVEEIIKK DIFRETPLRY LGYANEVGEA FRSLVKPVVV KFSYVVAFGY VAADSIDKGL  60
   61 QEYIKTHSTS TEKTKKVAIA AVDTVLWQTF ASVLIPGFTI NRFCFFSNLL LQKS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [115-429]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TKLPTNMRKW TVTCLGLATI PFIVHPIDSF VEEAMDKTAR KIYNKMNKIL RGVIQFRNTI  60
   61 RKDLVKQFEE IKNNPSPTAV MFTCMDSRML PTRFTQSQVG DMFVVRNAGN MIPDAPNYGA 120
  121 FSEVSVNTEP AALELAVKRG GIRHIVVCGH SDCKAINTLY GLHQCPKNFD VTSPMDHWVR 180
  181 RNGFASVKRL NERLHRGPSS MKFESEVAPS QSFDAIIDPM DTLAMEDKLS QINVLQQLIN 240
  241 ICSHEFLKEY LESGRLHIHG MWFDIYKGED YLFSKDKKRF VVIDEKTVTD LLAELNARYP 300
  301 VPEDQDGPVA FAKSN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 58.30103
Match: 1ddzA
Description: beta-carbonic anhydrase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
carbonate dehydratase activity 2.96380803089124 bayes_pls_golite062009
catalytic activity 1.85658156053797 bayes_pls_golite062009
carbon-oxygen lyase activity 1.691366175135 bayes_pls_golite062009
hydro-lyase activity 1.65497918079842 bayes_pls_golite062009
lyase activity 1.62374861994341 bayes_pls_golite062009
binding 1.30630421512737 bayes_pls_golite062009
protein binding 0.592567938703741 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle