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View Structure Prediction Details

Protein: pry-1
Organism: Caenorhabditis elegans
Length: 586 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pry-1.

Description E-value Query
Range
Subject
Range
gi|6653584 - gi|6653584|gb|AAF22799.1|AF205888_1 AXIN2 [Homo sapiens]
310.0 [0..4] [585..74]

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Predicted Domain #1
Region A:
Residues: [1-138]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 METHLGWARS LEAVLSDRSA LDAFQEWLIE YSSPQYLDLF FAIRAYERMA LEGKPEKSQL  60
   61 SKSIYSKFLS SRTGNCEAIP KHFRAPIGEK LRHGTELEDR VFSHCSNFVQ EFLRRQHEEF 120
  121 VGSEEFIEAF NKMSSTTA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 41.0
Match: 2jm5A
Description: No description for 2jm5A was found.

Predicted Domain #2
Region A:
Residues: [139-276]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DQLPGGSAHH SSHQNTMRRS SGTTSRKSAA QIATQLTAEA LLKSKHDRHS KLGETKLEKM  60
   61 YPPTRQPYVC NATTSHNDSA VSSTFSGDTP EAHRMHSNRL RHIRDEQARE NHGTMTLPRV 120
  121 EKASVDGQQW DHSSESGR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [277-503]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RNFAMEITRK LLRHIDKVKL NDEMEKRIDD IEECRYTTID MVNGTEPNDD LGKIDEDEEL  60
   61 DDYLKMKMTD DSQKGSTNRS PKGPAGEPNK SGEGSKNTTL SPTNRAPAQL HNTIRVPRRK 120
  121 DYPRDTSASL KSHRHHQIDT NRMMSQSMCA PSYSSASSSY SRDSFAPAPT TRVNFAPGSS 180
  181 KSSQFYDSSG IGSMAPSAFS ATSSLDYKDR RQHRKAPTPK KHSKIGK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [504-586]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLSNLITISY LGTDKIPVVT HVPNDGPMTL AEFKRHFALP NGAHQLFFKT ECEDGSAPFQ  60
   61 LLLIKDEHHL LPVFEGRIAA ELR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 28.0
Match: 1wspA
Description: Crystal structure of axin dix domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle