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View Structure Prediction Details

Protein: cah-4
Organism: Caenorhabditis elegans
Length: 280 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cah-4.

Description E-value Query
Range
Subject
Range
gi|35505160, gi|... - gi|40363537|ref|NP_954685.1| carbonic anhydrase II [Danio rerio], gi|35505160|gb|AAH57412.1| Carboni...
296.0 [0..26] [278..3]

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Predicted Domain #1
Region A:
Residues: [1-280]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPPQVRRSA RLSKRCQEEK VKLQKKNVGF KAKSKSAKKS NKKFKKAAAQ RQSPIDIVPQ  60
   61 HVCCDTDVCK ADALNIDYKS GDCCDVLVSE GGFLVNVKRN CGTFLTANHL PSSKFALAQF 120
  121 HAHWGSNSKE GSEHFLDGKQ LSGEVHFVFW NTSYESFNVA LSKPDGLAVV GVFLKEGKYN 180
  181 DNYHGLIDTV RKATGNATPI AMPKDFHIEH LLPSPDKREF VTYLGSLTTP PYNECVIWTL 240
  241 FTEPVEVSFG QLNVLRNIIP ANHRACQDRC DREIRSSFNF 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 79.522879
Match: 1ugbA
Description: HUMAN CARBONIC ANHYDRASE II[HCAII] (E.C.4.2.1.1) MUTANT WITH ALA 65 REPLACED BY GLY (A65G)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.59667704693142 bayes_pls_golite062009
protein binding 1.30419076438266 bayes_pls_golite062009
transition metal ion binding 0.36067052386032 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle