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View Structure Prediction Details

Protein: unc-73
Organism: Caenorhabditis elegans
Length: 633 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for unc-73.

Description E-value Query
Range
Subject
Range
unc-73 - guanine nucleotide exchange factor status:Confirmed UniProt:O61528 protein_id:AAC71108.1
383.0 [0..69] [631..1634]

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Predicted Domain #1
Region A:
Residues: [1-161]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRRSQTVEGS TDSEGGGGTT PTKSSKKERW SFAIKRRWFS SSTSRHSHDH DVAIVQPTKT  60
   61 TLGGTDNNNA ESGSVPDRPD DSNASGSTVS KRKSLRRIFA NSSKERAAAA NSSSSNNNSP 120
  121 ATRQSTSTSS PVTANGHTTE SSTSAPIGVL SSGEPTSSNS I

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.12
Match: 2j63A
Description: No description for 2j63A was found.

Predicted Domain #2
Region A:
Residues: [162-235]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSSSTPTHTV PSSVPATVIP IVVAEDEKAE DCLPPPMENI TINNSIDEKD MNEDSVAASD  60
   61 AVEPEVALPA KVEK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [236-633]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPEETARFKR SYVLMELVET EQDYVKDLTS VVEGYIGNLN KMDLPADLVG KDKIIFANIV  60
   61 NILEFHKTNF LKEIEKCSEN YEAAGAAFVK YERRLHTLYV TYCQNKPKSD YLLAQDDFEA 120
  121 FFADTKAKLG HKVALCDLLI KPVQRIMKYQ LLLKDILKFT ERAKDKTDTL KKALQVMHVV 180
  181 PKACDDMMQV GRLQNFDKSL SAQGKLIHQG TLQISESIAG NVQKPKDRRI FLFEQSAIIA 240
  241 DHIPPKKEFG NPTYIFKSQF MVNKMVFEPN VPDDPLRFVI KSSDPTQPTS FIANAQSQEE 300
  301 KDEWNRKMSE LLDQQKRLLA ALVDPRRYND MSSGMGDLSL GAPGGDRRGA PSSANRSAAS 360
  361 SSKKPAESPK KEGKSKSSLF SFGKKPAKSP TSPPPVGK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 67.221849
Match: 1kz7A
Description: Dbl's big sister, Dbs
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle