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View Structure Prediction Details

Protein: msi-1
Organism: Caenorhabditis elegans
Length: 320 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for msi-1.

Description E-value Query
Range
Subject
Range
gi|73974138 - gi|73974138|ref|XP_856875.1| PREDICTED: similar to Polyadenylate-binding protein 1 (Poly(A)-binding ...
233.0 [0..3] [319..143]

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Predicted Domain #1
Region A:
Residues: [1-242]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTTVSTGAT AVATLRETSP PVDGHEEARL NADSDDGSHG SQDPGKMFIG GLSWQTTAEN  60
   61 LRDYFGRFGE VNECMVMRDP ATKRARGFGF ITFVDPSSVD KVLNNREHEL DGKKIDPKVA 120
  121 FPKRTQAKLV TKTKKVFIGG LSATSTLEDM KQYFETYGKV EDAMLMFDKA TQRHRGFGFV 180
  181 TFDSDEVADK VCEIHFHEIN GKMVECKKAQ PKEVMLPVQL NKSRAAAARN LYGMPPETLL 240
  241 AY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 52.39794
Match: 1pgzA
Description: Crystal Structure of UP1 Complexed With d(TTAGGGTTAG(6-MI)G); A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6-MI)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 6.73097473547076 bayes_pls_golite062009
6.62953239642182 bayes_pls_golite062009
mRNA binding 5.29759606920196 bayes_pls_golite062009
nucleic acid binding 3.81920018903278 bayes_pls_golite062009
binding 3.44552682116509 bayes_pls_golite062009
snRNA binding 3.28448936696877 bayes_pls_golite062009
poly-pyrimidine tract binding 3.11990160533699 bayes_pls_golite062009
single-stranded RNA binding 2.93798024346416 bayes_pls_golite062009
U1 snRNA binding 2.26303528058407 bayes_pls_golite062009
structural molecule activity 1.29928829870122 bayes_pls_golite062009
transcription regulator activity 1.07788694919471 bayes_pls_golite062009
protein binding 1.02232785292059 bayes_pls_golite062009
DNA binding 0.978604858165557 bayes_pls_golite062009
mRNA 3'-UTR binding 0.591700155096213 bayes_pls_golite062009
transcription factor activity 0.234742017105535 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [243-320]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AQYLPRFGGN LMYPNFTNVF NNMPGGYSGL STPGGSSNRP PHQFDTASLY SLNNGGQLLD  60
   61 SQAQMFMNQQ SYHSHSKY

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle