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View Structure Prediction Details

Protein: unc-94
Organism: Caenorhabditis elegans
Length: 392 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for unc-94.

Description E-value Query
Range
Subject
Range
gi|47230640 - gi|47230640|emb|CAF99833.1| unnamed protein product [Tetraodon nigroviridis]
222.0 [0..32] [380..34]

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Predicted Domain #1
Region A:
Residues: [1-202]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQAKTDYYS EEKTFSAPSA NSQQGTQLPS KVYNKGLKDL EDNDIEGLLS SLSIDELEDL  60
   61 NNDFDPDNSM LPPSQRCRDQ TDKEPTGPYK RDNLLKFLED KAKTEKDWED VCPYTPGQKR 120
  121 GKVYDSDSGR NSEEPENGKM EMPIEIDLDD DEEELECALV TAPEKDLVDL AGILGMHNVL 180
  181 NQPQYYNALK GKTQDESTGT TF

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 9.920819
Match: PF03250.5
Description: No description for PF03250.5 was found.

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [203-392]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NGIMQSYVPR IVPDEPDNDT DVESCINRLR EDDTDLKEVN INNMKRVSKE RIRSLIEAAC  60
   61 NSKHIEKFSL ANTAISDSEA RGLIELIETS PSLRVLNVES NFLTPELLAR LLRSTLVTQS 120
  121 IVEFKADNQR QSVLGNQVEM DMMMAIEENE SLLRVGISFA SMEARHRVSE ALERNYERVR 180
  181 LRRLGKDPNV 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.09691
Match: 1pgvA
Description: Tropomodulin C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
microtubule minus-end binding 7.70887263207962 bayes_pls_golite062009
cytoskeletal protein binding 5.04595324782806 bayes_pls_golite062009
actin binding 4.98528043340021 bayes_pls_golite062009
tropomyosin binding 2.80631683562112 bayes_pls_golite062009
binding 2.665591019824 bayes_pls_golite062009
protein binding 2.66138763326419 bayes_pls_golite062009
myosin binding 1.32546860780591 bayes_pls_golite062009
tubulin binding 1.00494145757097 bayes_pls_golite062009
microtubule binding 0.854246295331667 bayes_pls_golite062009
catalytic activity 0.143741655309638 bayes_pls_golite062009
Ras GTPase activator activity 0.0986232864289136 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle