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View Structure Prediction Details

Protein: daf-16
Organism: Caenorhabditis elegans
Length: 510 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for daf-16.

Description E-value Query
Range
Subject
Range
daf-16 - status:Confirmed UniProt:O16850 protein_id:AAK82918.1
226.0 [0..1] [510..1]

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Predicted Domain #1
Region A:
Residues: [1-108]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMEMLVDQGT DASSSASTST SSVSRFGADT FMNTPDDVMM NDDMEPIPRD RCNTWPMRRP  60
   61 QLEPPLNSSP IIHEQIPEED ADLYGSNEQC GQLGGASSNG STAMLHTP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [109-228]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DGSNSHQTSF PSDFRMSESP DDTVSGKKTT TRRNAWGNMS YAELITTAIM ASPEKRLTLA  60
   61 QVYEWMVQNV PYFRDKGDSN SSAGWKNSIR HNLSLHSRFM RIQNEGAGKS SWWVINPDAK 120
  121 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 22.09691
Match: 1e17A
Description: Afx (Foxo4)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.835523092977445 bayes_pls_golite062009
transcription regulator activity 0.4843036104266 bayes_pls_golite062009
nucleic acid binding 0.37117756729668 bayes_pls_golite062009
DNA binding 0.3118855114645 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [229-510]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PGRNPRRTRE RSNTIETTTK AQLEKSRRGA KKRIKERALM GSLHSTLNGN SIAGSIQTIS  60
   61 HDLYDDDSMQ GAFDNVPSSF RPRTQSNLSI PGSSSRVSPA IGSDIYDDLE FPSWVGESVP 120
  121 AIPSDIVDRT DQMRIDATTH IGGVQIKQES KPIKTEPIAP PPSYHELNSV RGSCAQNPLL 180
  181 RNPIVPSTNF KPMPLPGAYG NYQNGGITPI NWLSTSNSSP LPGIQSCGIV AAQHTVASSS 240
  241 ALPIDLENLT LPDQPLMDTM DVDALIRHEL SQAGGQHIHF DL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle