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View Structure Prediction Details

Protein: unc-1
Organism: Caenorhabditis elegans
Length: 285 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for unc-1.

Description E-value Query
Range
Subject
Range
gi|50757151 - gi|50757151|ref|XP_415401.1| PREDICTED: similar to Erythrocyte band 7 integral membrane protein (Sto...
265.0 [0..11] [285..383]

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Predicted Domain #1
Region A:
Residues: [1-97]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNKERTEPQ WVTPSSNQDV PPDYETIGTI FGYALQALSW ILIIVTFPFS MCVCLKVIKE  60
   61 YERVVIFRIG RLVFGGARGP GMIFIIPCID TYRKIDL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [98-285]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RVVSYAVPPQ EILSKDSVTV SVDAVVYFRT SDPIASVNNV DDAIYSTKLL AQTTLRNALG  60
   61 MKTLTEMLTE REAIAQLCET ILDEGTEHWG VKVERVEVKD IRLPQQLTRA MAAEAEAARE 120
  121 ARAKVVAAEG EQKASRALKE AADVIQANPV ALQLRHLQAL NSIAAEHNST IVFPVPVEMF 180
  181 GAFMKKDQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.69897
Match: 1winA
Description: Solution Structure of the Band 7 Domain of the mouse Flotillin 2 Protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.52494198011598 bayes_pls_golite062009
protein binding 0.977368420595996 bayes_pls_golite062009
structural molecule activity 0.834496144484266 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle