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View Structure Prediction Details

Protein: unc-1
Organism: Caenorhabditis elegans
Length: 285 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for unc-1.

Description E-value Query
Range
Subject
Range
gi|50757151 - gi|50757151|ref|XP_415401.1| PREDICTED: similar to Erythrocyte band 7 integral membrane protein (Sto...
265.0 [0..11] [285..383]

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Predicted Domain #1
Region A:
Residues: [1-97]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNKERTEPQ WVTPSSNQDV PPDYETIGTI FGYALQALSW ILIIVTFPFS MCVCLKVIKE  60
   61 YERVVIFRIG RLVFGGARGP GMIFIIPCID TYRKIDL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [98-285]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RVVSYAVPPQ EILSKDSVTV SVDAVVYFRT SDPIASVNNV DDAIYSTKLL AQTTLRNALG  60
   61 MKTLTEMLTE REAIAQLCET ILDEGTEHWG VKVERVEVKD IRLPQQLTRA MAAEAEAARE 120
  121 ARAKVVAAEG EQKASRALKE AADVIQANPV ALQLRHLQAL NSIAAEHNST IVFPVPVEMF 180
  181 GAFMKKDQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.69897
Match: 1winA
Description: Solution Structure of the Band 7 Domain of the mouse Flotillin 2 Protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.52494198011598 bayes_pls_golite062009
protein binding 0.977368420595996 bayes_pls_golite062009
structural molecule activity 0.834496144484266 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle