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View Structure Prediction Details

Protein: unc-49
Organism: Caenorhabditis elegans
Length: 487 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for unc-49.

Description E-value Query
Range
Subject
Range
unc-49 - gamma-aminobutyric-acid receptor status:Confirmed UniProt:Q9Y0I4 protein_id:CAC42348.1
356.0 [0..1] [487..1]

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Predicted Domain #1
Region A:
Residues: [1-371]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MARPFTLIVL LSAHLCLHVV VTQDEDSHIN TQLLSSVLDR LTNRTTYDKR LRPRYGEKPV  60
   61 DVGITIHVSS ISAVSEVDMD FTLDFYMRQT WQDPRLAFGS LDLGLSKEID SLTVGVDYLD 120
  121 RLWKPDTFFP NEKKSFFHLA TTHNSFLRIE GDGTVYTSQR LTVTATCPMD LKLFPMDSQH 180
  181 CKLEIESYGY ETKDIDYYWG KKRTDLEITA VKFDTFQLPQ FQPTLYFVNT TKAETSSGKY 240
  241 VRLALEVILV RNMGFYTMNI VIPSILIVTI SWVSFWLNRE ASPARVGLGV TTVLTMTTLI 300
  301 TTTNNSMPKV SYVKGLDVFL NFCFVMVFAS LLEYAIVSYM NKRLVLRREK RRKAAEQQQR 360
  361 NEMPMFNASP K

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 63.0
Match: 2bg9A
Description: Refined structure of the nicotinic acetylcholine receptor at 4A resolution.
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [372-487]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AANNNADLYF AGHNSSMNPL MEIPENCDCR TIPMMQHPRL VTDGAHTLWP APFARPKKAS  60
   61 KTCCQRWTPA KIDKLSRYGF PLSFSIFNIV YWLYMKYLSL NSSDKIQEND KWQQIH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 31.69897
Match: 1oedA
Description: Acetylcholine receptor protein, alpha chain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle