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View Structure Prediction Details

Protein: daf-12
Organism: Caenorhabditis elegans
Length: 267 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for daf-12.

Description E-value Query
Range
Subject
Range
gi|114627460 - gi|114627460|ref|XP_520345.2| PREDICTED: hypothetical protein [Pan troglodytes]
214.0 [0..8] [266..345]

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Predicted Domain #1
Region A:
Residues: [1-267]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTPTHGFQYQ SDPYQVPPAE RNINYQLNAA ELKALDAVRE AFYGMDDPME QGRQMQSFLK  60
   61 ANKTPADIMN IMDVTMRRFV KVAKGVPAFR EVSQEGKFSL LKGGMIEMLT VRGVTRYDAS 120
  121 TNSFKTPTIK GQNVSVNVDD MFAKLNANAQ AQKAKCLEFF GFFDEEIKKN ELAVYLVMLA 180
  181 VLFSVRSDPP MNENDVRIVT ERHNHFMSLL NRYLESLFGE QARRIFERIP KALGLLNEIA 240
  241 RNAGMLFMGT VRSGEAEELP GEFFKIK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 53.39794
Match: 1lbdA
Description: LIGAND-BINDING DOMAIN OF THE HUMAN NUCLEAR RECEPTOR RXR-ALPHA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.15996699473685 bayes_pls_golite062009
transcription regulator activity 0.46162010671465 bayes_pls_golite062009
protein binding 0.33427459029264 bayes_pls_golite062009
nucleic acid binding 0.15459949087509 bayes_pls_golite062009
DNA binding 0.14395376162921 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle