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View Structure Prediction Details

Protein: spe-9
Organism: Caenorhabditis elegans
Length: 661 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for spe-9.

Description E-value Query
Range
Subject
Range
gi|68440657 - gi|68440657|ref|XP_688293.1| PREDICTED: similar to secreted protein SST3 [Danio rerio]
382.0 [0..20] [638..2016]

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Predicted Domain #1
Region A:
Residues: [1-179]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNVILVLVVL FFAGDCAKIR KIIDFLEKDA PNDIEKTPNY NEESLAVKRN KNFNPCLENP  60
   61 KICSNRGKCL HENGNFYCIC PVTHYGKTCE HVSDQTNCEK HLCQNNSTCV SIKSLRTIVN 120
  121 TVLLRQIRVQ RKVNGSKAAL TNEELAEIDL EVNYECICQK GYFGGLCDES EADRTCQEV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.522879
Match: 1tozA
Description: NMR structure of the human NOTCH-1 ligand binding region
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [180-549]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YCLGRGKGAI NATGKCECEC ENQFFGDRCE QISACFDTQC DNGGICEDVV DWKTKTVTAT  60
   61 CKCPSAIELI GGTVTGENCE TLQIPSTAPK EFIPCAEGSN STMFFKKFIA NISLEYMDDI 120
  121 SELEAIKNDY NDGKNVNGTM TDGWCRNDGK CVPEVVRVNS SRAYYIYRCE CTNPLTDGYY 180
  181 CEYKRHDSCS LTREEVARGD RWDEKCTDSQ HGACVDISGV AHCVCKPDYT GEKCEIFDPC 240
  241 ARQPCKHGDC IPIPNTADVA FGTSRYQCLC PLSAKLNPES QACMEINEKK CAPGACGNGR 300
  301 CVPCESDADD LMPLCNDNDN RQGFRCLCEA GYLPPFCKVH TNPCYQNLCQ NSATCHIDPK 360
  361 QRSYDCQCVN 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.045757
Match: 1n7dA
Description: Low density lipoprotein (LDL) receptor YWTD domain; Low density lipoprotein (LDL) receptor, different EGF domains; Ligand-binding domain of low-density lipoprotein receptor
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein binding 1.27345206371464 bayes_pls_golite062009
binding 1.17619965960956 bayes_pls_golite062009
receptor binding 0.74474413948438 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [550-661]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GTRGSLCENV DDSCDAFGNK ICVHGTCIND EYFHRGFSCE CDDGFEGLDC NVEIAWSSVM  60
   61 TNRLMKNYEF SLPLVACFVS LAILLPVIVI SRRRQGRVEE AKKTSEVKTE NP

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.15
Match: 2go59
Description: No description for 2go59 was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle