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View Structure Prediction Details

Protein: CE27040
Organism: Caenorhabditis elegans
Length: 575 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE27040.

Description E-value Query
Range
Subject
Range
gi|49527412 - gi|49527412|emb|CAG61052.1| unnamed protein product [Candida glabrata]
gi|50291337, gi|... - gi|50291337|ref|XP_448101.1| unnamed protein product [Candida glabrata], gi|49527412|emb|CAG61052.1|...
288.0 [0..52] [574..73]

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Predicted Domain #1
Region A:
Residues: [1-94]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKFDDFLFTY LGEMGKYQKI QFFLVCLPTI VVSMHALSWT FASVDTPYRC RLPSDLPEKE  60
   61 PYYTTLLNFT KCTNDADANV PISEYGKPGV TCHY

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [95-575]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DRCTLPDNET CHEHIFDHSK VEYTAVQRWE ITCDRSWIKA TIQAAYYVGQ MAGSTTFGML  60
   61 GDRIGRKKVF FLAIVIQITC AYLIAIAPYW WLYALARAGT GFSHPGIFVI AVVIGMELVG 120
  121 PKYRKLASVI TGLFFALGQI FLGIEAIYFT NYQILHVVIA SPALLFLSYC QKSAKNRKKI 180
  181 DFANFLADFL LKNRFFFSRW LVPESARWLV SQKRYKEADE VLQKAASVNG TVLPENWWEQ 240
  241 LDDSTTGGGG APGAPTKKLT GADLFRTPEL RKRTLVVFFL WPVISMVYYG MAMKANVLGG 300
  301 DIYVNFIFAA FVEIPALFIV YLLIDRIGRR LILAGGLFIA GACLLVNWLM GDNVQLWMAI 360
  361 TQMAFTKGSI TGVYAAIYTY SPELFPTVIR NTAMGFCSTI ARVGAIAASY ISMWIAEQFG 420
  421 KVFMIIPFGC MAVLAAVMTL LFLPETMGKP LPESIEEIEE GDSYRSSHEM QPLSKSTEET 480
  481 A

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.045757
Match: 1pw4A
Description: Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
substrate-specific transmembrane transporter activity 5.46247398538901 bayes_pls_golite062009
ion transmembrane transporter activity 4.58978526526921 bayes_pls_golite062009
cation transmembrane transporter activity 4.31967711223954 bayes_pls_golite062009
transporter activity 4.09176719149278 bayes_pls_golite062009
anion transmembrane transporter activity 3.94605227012838 bayes_pls_golite062009
substrate-specific transporter activity 3.59744164024479 bayes_pls_golite062009
transmembrane transporter activity 3.5865018981083 bayes_pls_golite062009
organic anion transmembrane transporter activity 3.3413526350788 bayes_pls_golite062009
inorganic anion transmembrane transporter activity 2.52916479889426 bayes_pls_golite062009
hexose phosphate transmembrane transporter activity 2.39244854801368 bayes_pls_golite062009
glucose-6-phosphate transmembrane transporter activity 2.39244854801368 bayes_pls_golite062009
organic acid transmembrane transporter activity 2.15783210522667 bayes_pls_golite062009
active transmembrane transporter activity 1.59419818573076 bayes_pls_golite062009
binding 1.46605775041083 bayes_pls_golite062009
secondary active transmembrane transporter activity 1.22264637452409 bayes_pls_golite062009
polyol transmembrane transporter activity 0.924836669821548 bayes_pls_golite062009
alcohol transmembrane transporter activity 0.924836669821548 bayes_pls_golite062009
glycerol transmembrane transporter activity 0.812001619402678 bayes_pls_golite062009
symporter activity 0.74591237387473 bayes_pls_golite062009
solute:cation symporter activity 0.74591237387473 bayes_pls_golite062009
phosphate transmembrane transporter activity 0.312628600969375 bayes_pls_golite062009
cation:sugar symporter activity 0.143419068761182 bayes_pls_golite062009
sugar:hydrogen symporter activity 0.143419068761182 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle