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View Structure Prediction Details

Protein: lin-22
Organism: Caenorhabditis elegans
Length: 173 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for lin-22.

Description E-value Query
Range
Subject
Range
gi|37590864, gi|... - gi|37590864|gb|AAH59551.1| Her6 protein [Danio rerio], gi|169158177|emb|CAQ13541.1| hairy-related 6 ...
128.0 [0..2] [171..15]

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Predicted Domain #1
Region A:
Residues: [1-173]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSFLCSDTE IESDGGISRC KKIKNKPLME KKRRARINKS LSQLKQILIQ DEHKNSIQHS  60
   61 KWEKADILEM AVEYLQQLRS AQPCSLSPST SSISTPPTPK EEIRNIKVPL NPIASFLNPM 120
  121 MQQYVAYQQL AQLSMYTQLF NNPAGVPLRA DAGVTAQSPE LAEKLKIEDR SRV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.522879
Match: 1am9A
Description: SREBP-1a
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.04189889011459 bayes_pls_golite062009
DNA binding 1.34047429825414 bayes_pls_golite062009
transcription regulator activity 1.24166705689751 bayes_pls_golite062009
transcription factor activity 1.21289741269658 bayes_pls_golite062009
nucleic acid binding 1.12120276328559 bayes_pls_golite062009
protein binding 0.90375176425983 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle