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View Structure Prediction Details

Protein: CE25073
Organism: Caenorhabditis elegans
Length: 446 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE25073.

Description E-value Query
Range
Subject
Range
gi|23092863, gi|... - gi|24656434|ref|NP_647768.2| CG1869-PA [Drosophila melanogaster], gi|23092863|gb|AAF47714.2| CG1869-...
324.0 [0..85] [444..123]

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Predicted Domain #1
Region A:
Residues: [1-78]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKQDNKNEI VAPSIHGKKL DRSLWRIYLK YIVIAIVLLV VLGNTIMTII LVVNDVNETG  60
   61 STPTVTSISS TVAASTYP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [79-446]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ATPGCNKRII GYYFATQTSV ITRDQVSKLT HAVFAFVNMT SDGHLQIDGD LAKNRFTNLI  60
   61 EIAKQQTPQV KVMISIGGND NSNNFKPVLS SPDRKKLFIN STVSFLQTYD IDGVDLYWKW 120
  121 PGKTSKDIYS QFINDLRYSL QRQKRNYIMS IVLPPPDMGA NYEAGIDIEN IFDNVDFLNI 180
  181 FTMGYFGPWQ NDAGMITGAA SQLFNGVNGV PGRKTYNIHH STERYVCKTG QSDKYNIAIP 240
  241 FYTMLWKHVK GPVNPPNIEI YRNATFQGGV VGETSMSRKL VQEEGYDFSN PTYNPEIRAA 300
  301 FKYNATTETF LTFETNDTIA AKIDYVKDRI LGGVWIWAVD MDDDSNNLLN LVKFTGYCTV 360
  361 GNLTLYNC

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 85.39794
Match: 1wawA
Description: Specificity and affnity of natural product cyclopentapeptide inhibitor Argadin against human chitinase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
growth factor activity 0.34357571678721 bayes_pls_golite062009
receptor binding 0.21634641574378 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle