






| Protein: | hpl-2 |
| Organism: | Caenorhabditis elegans |
| Length: | 303 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for hpl-2.
| Description | E-value | Query Range |
Subject Range |
|
|
255.0 | [0..1] | [303..1] |
|
Region A: Residues: [1-177] |
1 11 21 31 41 51
| | | | | |
1 MSSKSTKRAK IEDPKDNVFM VEKVLDKRTG KAGRDEFLIQ WQGFPESDSS WEPRENLQCV 60
61 EMLDEFEREF SKREKPIRKR HSQKPEPSED QADPEEDKDE KKETNQNDKF SLEGKQLKCI 120
121 VGLTKGPGEL HFLCKFSDDT ARLLPAKEVN SRYRPFVDAY GEFLKKKMER RHKRISE
|
| Detection Method: | |
| Confidence: | 24.0 |
| Match: | 2b2uA |
| Description: | Tandem chromodomains of human CHD1 complexed with Histone H3 Tail containing trimethyllysine 4 and dimethylarginine 2 |
Matching Structure (courtesy of the PDB):![]() |
|
| Term | Confidence | Notes |
| transcription repressor activity | 4.08500855631983 | bayes_pls_golite062009 |
| transcription regulator activity | 3.64390820819794 | bayes_pls_golite062009 |
| methylated histone residue binding | 3.42338304360938 | bayes_pls_golite062009 |
| chromatin binding | 3.1924157640698 | bayes_pls_golite062009 |
| binding | 3.06758476214113 | bayes_pls_golite062009 |
| nucleic acid binding | 2.19167058827256 | bayes_pls_golite062009 |
| DNA binding | 2.05514577638135 | bayes_pls_golite062009 |
| histone binding | 2.00388175060339 | bayes_pls_golite062009 |
| protein binding | 1.61683263008775 | bayes_pls_golite062009 |
| general transcriptional repressor activity | 0.75184432495983 | bayes_pls_golite062009 |
| transcription corepressor activity | 0.294457188332415 | bayes_pls_golite062009 |
| catalytic activity | 0.14067200158938 | bayes_pls_golite062009 |
| transcription activator activity | 0.136090220479238 | bayes_pls_golite062009 |
|
Region A: Residues: [178-303] |
1 11 21 31 41 51
| | | | | |
1 GKKKRSIEED DADDEWPEMP PGHRILTTEE HELQRRKESK ISQDVEMTEA FQQTAADMLN 60
61 DMHMAANGDL LSSFPQDFLE DSGDGEVHEA AILSVFDDNS NSPPPCPIVV DTVPDDDDSL 120
121 LFPRNS
|
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.