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View Structure Prediction Details

Protein: mex-3
Organism: Caenorhabditis elegans
Length: 415 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mex-3.

Description E-value Query
Range
Subject
Range
gi|1644450 - gi|1644450|gb|AAC47313.1| MEX-3 [Caenorhabditis elegans]
308.0 [0..1] [415..1]

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Predicted Domain #1
Region A:
Residues: [1-123]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKEEQIAYKL PGAWYYEEDT ASCSPVSDPE DIAQFLNYRT SIGVQNVTES VEVPTSEHVA  60
   61 EIVGRQGCKI KALRAKTNTY IKTPVRGEDP IFVVTGRLED VNEAKREIDC AAEHFTQIRA 120
  121 SRR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.221849
Match: 1x4nA
Description: Solution structure of KH domain in FUSE binding protein 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleic acid binding 2.76562424828414 bayes_pls_golite062009
binding 2.12000404411947 bayes_pls_golite062009
mRNA binding 1.67623463602459 bayes_pls_golite062009
RNA binding 1.5640739272938 bayes_pls_golite062009
transcription regulator activity 0.573444640703857 bayes_pls_golite062009
catalytic activity 0.483552478758071 bayes_pls_golite062009
protein binding 0.446932489882167 bayes_pls_golite062009
DNA binding 0.219740042471452 bayes_pls_golite062009
transcription repressor activity 0.0918327634805927 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [124-206]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HTQVVPGAHA PGQITSYVRV PLRVVGLVVG PKGATIKRIQ QDTHTYIITP SREREPVFEV  60
   61 TGLPHNVEAA RKEIETHIFQ RTG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.69897
Match: 2dgrA
Description: No description for 2dgrA was found.

Predicted Domain #3
Region A:
Residues: [207-415]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLPETDNDFA GQLAGVSLMV QKQQQAQQQM QEAQQQSMFY RRAFGNSNPF NQKEMSSSPF  60
   61 GMESSLGLDA LLRSFPSMRS SLTPESLSGT GLSSRPSLGG GQSAKQDLPT YDYWGTNNSL 120
  121 NDIMENEILS RKYDALSAWS SMGLEKREES PTNGLMSSLK GTSAGFGLLS TIWSGGNMNL 180
  181 SPGSLASASA SPTSSTCDHN DHTLVPING

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle